Browse our anti-Chromosome 6 Open Reading Frame 150 (C6orf150) Antibodies

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anti-Chromosome 6 Open Reading Frame 150 Antibodies (C6orf150)
On www.antibodies-online.com are 41 Chromosome 6 Open Reading Frame 150 (C6orf150) Antibodies from 8 different suppliers available. Additionally we are shipping Chromosome 6 Open Reading Frame 150 Proteins (5) and many more products for this protein. A total of 50 Chromosome 6 Open Reading Frame 150 products are currently listed.
Synonyms:
C6orf150, cGAS, h-cGAS
list all antibodies Gene Name GeneID UniProt
C6orf150 115004 Q8N884
C6orf150    
C6orf150    

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Top referenced anti-Chromosome 6 Open Reading Frame 150 Antibodies

  1. Cow (Bovine) Polyclonal C6orf150 Primary Antibody for WB - ABIN2785007 : Rush, Moritz, Lee, Guo, Goss, Spek, Zhang, Zha, Polakiewicz, Comb: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. in Nature biotechnology 2005 (PubMed)
    Show all 2 references for 2785007

  2. Human Polyclonal C6orf150 Primary Antibody for EIA, WB - ABIN950947 : Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: The DNA sequence and analysis of human chromosome 6. ... in Nature 2003 (PubMed)
    Show all 2 references for 950947

More Antibodies against Chromosome 6 Open Reading Frame 150 Interaction Partners

Human Chromosome 6 Open Reading Frame 150 (C6orf150) interaction partners

  1. Type I IFN is detrimental to the host, and dysregulation of iron homeostasis genes may explain lower bacteria survival in cGAS(-/-) and TLR4 (show TLR4 Antibodies)(-/-) cells.

  2. the current study demonstrated that the DNA sensor cGAS is dynamically modified by SUMO

  3. while IFI16 (show IFI16 Antibodies) induces cytokines, only cGAS activates STING/TBK-1 (show TBK1 Antibodies)/IRF3 (show IRF3 Antibodies) and apoptotic responses upon herpes simplex virus 1 and human cytomegalovirus infections; findings show that IFI16 (show IFI16 Antibodies), not cGAS or PML (show PML Antibodies), represses HSV-1 gene expression, reducing virus

  4. cGAs recognizes bacterial/viral DNA, and is a strong activator of STING that can further activate IRF3 (show IRF3 Antibodies) and subsequent type I interferon (show IFNA Antibodies) production. (Review)

  5. Data suggest that the N terminus enhanced the activity of core-cyclic GMP (show NT5C2 Antibodies)-AMP (show APRT Antibodies) synthase (cGAS) by facilitating formation of a monomeric complex of cGAS and DNA.

  6. Primary human endothelial cells mount robust type I interferon (show IFNA Antibodies) responses to human cytomegalovirus that are dependent upon cyclic GMP (show NT5C2 Antibodies)-AMP (show APRT Antibodies) synthase (cGAS), STING, and interferon regulatory factor 3 (IRF3 (show IRF3 Antibodies)) signaling.

  7. cGAS and STING are intracellular sensors that activate the interferon (show IFNA Antibodies) pathway in response to virus infection. [review]

  8. cGAS silencing inhibited production of proinflammatory cytokines and matrix metalloproteinases (MMPs) as well as AKT (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) phosphorylation in TNFalpha (show TNF Antibodies)-stimulated fibroblast-like synoviocytes

  9. A STING-dependent, cGAS-independent pathway important for full interferon (show IFNA Antibodies) production and antiviral control of enveloped RNA viruses.

  10. By directly binding to cGAS, LANA, and particularly, a cytoplasmic isoform, inhibit the cGAS-STING-dependent phosphorylation of TBK1 (show TBK1 Antibodies) and IRF3 (show IRF3 Antibodies) and thereby antagonize the cGAS-mediated restriction of KSHV lytic replication.

Chromosome 6 Open Reading Frame 150 (C6orf150) Antigen Profile

Antigen Summary

Exhibits broad antiviral activity, most probably causing an early viral translation block.

Alternative names and synonyms associated with Chromosome 6 Open Reading Frame 150 (C6orf150)

  • chromosome 6 open reading frame 150 (C6orf150) antibody
  • Mab-21 domain containing 1 (MB21D1) antibody
  • C6orf150 antibody
  • cGAS antibody
  • h-cGAS antibody

Protein level used designations for C6orf150

chromosome 6 open reading frame 150 , cGAMP synthase , cyclic GMP-AMP synthase , mab-21 domain-containing protein 1 , protein MB21D1

GENE ID SPECIES
421864 Gallus gallus
100137406 Papio anubis
115004 Homo sapiens
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