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PYCARD Proteins

(PYD and CARD Domain Containing (PYCARD))
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Active filters:

  • Target: PYCARD
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7552364
PYCARD Protein (AA 1-195) (His tag) PYCARD · Protein Human HEK-293 Cells
  • PS (Protein Structure: Validation image available)
starts at $12,595.45 View price
  • 1 mg
Delivery in 41 to 67 Business Days Shipping to: United States
ABIN7565022
PYCARD Protein (AA 1-193) (His tag) PYCARD · Protein Mouse HEK-293 Cells
  • PS (Protein Structure: Validation image available)
starts at $12,595.45 View price
  • 1 mg
Delivery in 41 to 67 Business Days Shipping to: United States
ABIN1316968
PYCARD Protein (AA 1-149) (GST tag) PYCARD · Protein Human Wheat germ
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$475.39 View price
  • 10 μg
  • 25 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN3137154
PYCARD Protein (AA 1-193) (Strep Tag) PYCARD · Protein Mouse Cell-free protein synthesis (CFPS)
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
starts at $19,692.86 View price
  • 0.5 mg
  • 0.5 mg
Delivery in 55 to 67 Business Days Shipping to: United States
ABIN7575016
PYCARD Protein (His tag) PYCARD · Protein Human Escherichia coli (E. coli)
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
$345.09 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7890105
PYCARD Protein (AA 12-162) (His tag) PYCARD · Protein Human Escherichia coli (E. coli)
$427.29 View price
  • 50 μg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN3089316
PYCARD Protein (AA 1-195) (Strep Tag) PYCARD · Protein Human Cell-free protein synthesis (CFPS)
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
starts at $19,692.86 View price
  • 0.5 mg
  • 0.5 mg
Delivery in 55 to 67 Business Days Shipping to: United States
ABIN2730218
PYCARD Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag) PYCARD · Protein Human HEK-293 Cells
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
$1,112.40 View price
  • 20 μg
Delivery in 11 to 12 Business Days Shipping to: United States
ABIN2713165
PYCARD Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) PYCARD · Protein Human HEK-293 Cells
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
$1,112.40 View price
  • 20 μg
Delivery in 11 to 12 Business Days Shipping to: United States
ABIN2713166
PYCARD Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) PYCARD · Protein Human HEK-293 Cells
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
$1,112.40 View price
  • 20 μg
Delivery in 11 to 12 Business Days Shipping to: United States
ABIN1646663
PYCARD Protein (AA 1-203) (His tag) PYCARD · Protein Zebrafish (Danio rerio) Yeast
  • ELISA (ELISA: Listed application)
$2,669.83 View price
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7590748
PYCARD Protein (AA 1-195) (His tag) PYCARD · Protein Cow Yeast
  • ELISA (ELISA: Listed application)
$1,204.47 View price
  • 100 μg
  • 1 mg
Delivery in 60 to 72 Business Days Shipping to: United States
ABIN7945951
PYCARD Protein (His tag) PYCARD · Protein Human Escherichia coli (E. coli)
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
$478.00 View price
  • 100 μg
  • 1 mg
  • 50 μg
Delivery in 8 to 12 Business Days Shipping to: United States
Protein
  • PS (Protein Structure: Validation image available)
Grade
custom-made
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7552364
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 41 to 67 Business Days
Protein
  • PS (Protein Structure: Validation image available)
Grade
custom-made
Origin
Mouse
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Catalog No. ABIN7565022
starts at
$12,595.45
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 41 to 67 Business Days
Protein
  • AP (Affinity Purification: Listed application)
  • AA (Antibody Array: Listed application)
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Wheat germ
Protein Type
Recombinant
Catalog No. ABIN1316968
$475.39
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Grade
custom-made
Origin
Mouse
Host
Cell-free protein synthesis (CFPS)
Protein Type
Recombinant
Purity
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3137154
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
0.5 mg
Shipping to: United States
Delivery in 55 to 67 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7575016
$345.09
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7890105
$427.29
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
Grade
custom-made
Origin
Human
Host
Cell-free protein synthesis (CFPS)
Protein Type
Recombinant
Purity
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
Catalog No. ABIN3089316
starts at
$19,692.86
Plus shipping costs $50.00, if applicable $20.00 dry ice
0.5 mg
Shipping to: United States
Delivery in 55 to 67 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2730218
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2713165
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days
Protein
  • WB (Western Blotting: Validation image available)
  • AbP (Antibody Production: Listed application)
  • STD (Standard: Listed application)
Origin
Human
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 80 % as determined by SDS-PAGE and Coomassie blue staining
Catalog No. ABIN2713166
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Delivery in 11 to 12 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Zebrafish (Danio rerio)
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN1646663
$2,669.83
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
Cow
Host
Yeast
Protein Type
Recombinant
Purity
> 90 %
Catalog No. ABIN7590748
$1,204.47
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 72 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • SDS (SDS-PAGE: Listed application)
  • WB (Western Blotting: Listed application)
  • Imm (Immunogen: Listed application)
Origin
Human
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Catalog No. ABIN7945951
$478.00
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 12 Business Days

Latest Publications for our PYCARD Proteins

Shi, Wang, Li, Zhan, Tang, Fina, Su, Pratt, Bu, Hildebrand, Lyon, Scott, Quan, Sun, Russell, Arnett, Jurek, Chen, Kravchenko, Mathison, Moresco, Monson, Ulevitch, Beutler: "NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component." in: Nature immunology, Vol. 17, Issue 3, pp. 250-8, (2016) (PubMed).

Aliases for PYCARD Proteins

PYD and CARD domain containing (PYCARD) Proteins
PYD and CARD domain containing (Pycard) Proteins
PYD and CARD domain containing (pycard) Proteins
9130417A21Rik Proteins
ASC Proteins
Asc Proteins
asc1 Proteins
CARD5 Proteins
masc Proteins
TMS Proteins
TMS-1 Proteins
TMS1 Proteins
TNS1 Proteins
zAsc Proteins
zgc:109874 Proteins
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