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Toll-like receptor 3 (TLR3 (show TLR3 Proteins)) signaling requires TLR4 Interactor with leucine-rich REPeats (TRIL)
these data uncover TRIL as a mediator of innate immune responses within the brain, where it enhances neuronal cytokine responses to infection.
TRIL is a novel component of the TLR4 (show TLR4 Proteins) complex which may have particular relevance for the functional role of TLR4 (show TLR4 Proteins) in the brain
TRIL is a component of the TLR4 (MIM 603030) complex and is induced in a number of cell types by lipopolysaccharide (LPS) (Carpenter et al., 2009
TLR4 interactor with leucine rich repeats