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Browse our anti-HNF4A (HNF4A) Antibodies

Full name:
anti-Hepatocyte Nuclear Factor 4, alpha Antibodies (HNF4A)
On www.antibodies-online.com are 181 Hepatocyte Nuclear Factor 4, alpha (HNF4A) Antibodies from 25 different suppliers available. Additionally we are shipping HNF4A Kits (22) and HNF4A Proteins (13) and many more products for this protein. A total of 235 HNF4A products are currently listed.
Synonyms:
CG9310, dHNF-4, dHNF4, Dmel\\CG9310, DmHNF4, fb58h09, Hnf-4, HNF-4(D), HNF-4alpha, Hnf-4h, hnf4, HNF4A, HNF4a7, HNF4a8, HNF4a9, Hnf4alpha, id:ibd1279, MODY, MODY1, nr2a1, NR2A4, NR2A21, TCF, TCF14, wu:fb58h09
list all antibodies Gene Name GeneID UniProt
HNF4A 15378 P49698
HNF4A 25735 P22449
HNF4A 3172 P41235

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Most Popular Reactivities for anti-HNF4A (HNF4A) Antibodies

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anti-Mouse (Murine) HNF4A Antibodies:

anti-Rat (Rattus) HNF4A Antibodies:

anti-Human HNF4A Antibodies:

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Top referenced anti-HNF4A Antibodies

  1. Human Polyclonal HNF4A Primary Antibody for EIA, WB - ABIN357941 : Sugai, Umezu, Yamamoto, Jiang, Iwanari, Tanaka, Hamakubo, Kodama, Naito: Expression of hepatocyte nuclear factor 4 alpha in primary ovarian mucinous tumors. in Pathology international 2008 (PubMed)
    Show all 4 references for ABIN357941

  2. Human Polyclonal HNF4A Primary Antibody for WB - ABIN2777514 : Weedon, Owen, Shields, Hitman, Walker, McCarthy, Love-Gregory, Permutt, Hattersley, Frayling: Common variants of the hepatocyte nuclear factor-4alpha P2 promoter are associated with type 2 diabetes in the U.K. population. in Diabetes 2004 (PubMed)
    Show all 4 references for ABIN2777514

  3. Human Polyclonal HNF4A Primary Antibody for EIA, WB - ABIN357940 : Lee, Cha, Jung, Shon, Kim, Yeo, Shin: Genetic polymorphism of hepatocyte nuclear factor-4alpha influences human cytochrome P450 2D6 activity. in Hepatology (Baltimore, Md.) 2008 (PubMed)
    Show all 3 references for ABIN357940

  4. Human Polyclonal HNF4A Primary Antibody for EIA, IF - ABIN952766 : Lundblad, Eliasson: Silent myocardial infarction in women with impaired glucose tolerance: the Northern Sweden MONICA study. in Cardiovascular diabetology 2005 (PubMed)
    Show all 2 references for ABIN952766

  5. Human Polyclonal HNF4A Primary Antibody for ELISA, WB - ABIN185378 : Damcott, Hoppman, Ott, Reinhart, Wang, Pollin, OConnell, Mitchell, Shuldiner: Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish. in Diabetes 2004 (PubMed)

  6. Human Polyclonal HNF4A Primary Antibody for FACS, IF - ABIN389269 : Furuta, Iwasaki, Oda, Hinokio, Horikawa, Yamagata, Yano, Sugahiro, Ogata, Ohgawara, Omori, Iwamoto, Bell: Organization and partial sequence of the hepatocyte nuclear factor-4 alpha/MODY1 gene and identification of a missense mutation, R127W, in a Japanese family with MODY. in Diabetes 1997 (PubMed)

  7. Chicken Polyclonal HNF4A Primary Antibody for WB - ABIN2782264 : Holmkvist, Almgren, Lyssenko, Lindgren, Eriksson, Isomaa, Tuomi, Nilsson, Groop: Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes. in Diabetes 2008 (PubMed)

  8. Human Polyclonal HNF4A Primary Antibody for WB - ABIN389268 : Hong, Varanasi, Yang, Leff: AMP-activated protein kinase regulates HNF4alpha transcriptional activity by inhibiting dimer formation and decreasing protein stability. in The Journal of biological chemistry 2003 (PubMed)

More Antibodies against HNF4A Interaction Partners

Fruit Fly (Drosophila melanogaster) Hepatocyte Nuclear Factor 4, alpha (HNF4A) interaction partners

  1. Drosophila HNF4 mutants display diabetic phenotypes similar to those of sir2 (show SIRT1 Antibodies) mutants, and protein levels for dHNF4 are reduced in sir2 (show SIRT1 Antibodies) mutant animals. Sir2 (show SIRT1 Antibodies) exerts these effects by deacetylating and stabilizing dHNF4 through protein interactions.

  2. Results support a feed-forward model for dHNF4, in which fatty acids released from triglycerides activate the receptor, inducing enzymes that drive fatty acid oxidation for energy production.

Mouse (Murine) Hepatocyte Nuclear Factor 4, alpha (HNF4A) interaction partners

  1. Berberine has an effect on hepatic gluconeogenesis and lipid metabolism and is mediated through HNF-4alpha and regulated downstream of miR122

  2. Diminished XBP1 (show XBP1 Antibodies) and/or HNF4alpha in beta-cells led to impaired endoplasmic reticulum calcium homeostasis.

  3. In conclusion, our study revealed a novel mechanism by which TSH regulated the hepatic HNF-4alpha subcellular localization.

  4. an integrated analytic strategy was applied to identify the HNF4alpha-centered regulatory network.

  5. Tfr2 (show TFR2 Antibodies) is a novel target gene for HNF4alpha, and hepatic HNF4alpha plays a critical role in iron homeostasis.

  6. The miR (show MLXIP Antibodies)-34a-HNF4alpha pathway is activated under common conditions of metabolic stress and may have a role in the pathogenesis of NAFLD (show TSC2 Antibodies) and in regulating plasma lipoprotein metabolism.

  7. FOXA3 (show FOXA3 Antibodies) and HNF4alpha are powerful transcription factors for inducing rat bone marrow mesenchymal stem cells to differentiate into functional hepatocyte-like cells.

  8. HNF4a is involved in the downregulation of SHBG (show SHBG Antibodies) during obesity development.

  9. Results showed that HNF4a is highly expressed in brain of mouse model of major depression suggesting that this gene may be both essential for life and have a critical impact on physiological homeostasis under depressive status.

  10. These results suggest that the flavonoid luteolin ameliorates an atherogenic lipid profile in vivo that is likely to be mediated through the inactivation of HNF4alpha.

Human Hepatocyte Nuclear Factor 4, alpha (HNF4A) interaction partners

  1. PHD2 (show EGLN1 Antibodies) suppresses the activity of TGF-beta1 (show TGFB1 Antibodies) pathway and consequently maintains the expression of hepatocyte nuclear factor-4alpha

  2. rejected the hypothesis that all human MODY-associated mutations in HNF1A (show HNF1A Antibodies) / HNF4A induce changes in the pharmacokinetics of sulfonylureas in humans analogically to the Hnf1a (show HNF1A Antibodies)(-/-) mouse model

  3. Results showed that HNF4a is downregulated in colon carcinoma patients and its ectopic expression inhibited proliferation, migration and invasion of HT29, LoVo and SW480 cells.

  4. ETS2 (show ETS2 Antibodies), HNF4A and JUNB (show JUNB Antibodies) are synergistic master regulators of epithelial-to-mesenchymal transition in cancer.

  5. Berberine has an effect on hepatic gluconeogenesis and lipid metabolism and is mediated through HNF-4alpha and regulated downstream of miR122

  6. In conclusion, our study revealed a novel mechanism by which TSH regulated the hepatic HNF-4alpha subcellular localization.

  7. Galpha12 overexpression in HCC inhibits MIR122 transactivation by inactivating HNF4alpha, which causes c-Met induction, contributing to cancer aggressiveness.

  8. We identified hepatocyte nuclear factor 4alpha as a regulatory factor that bound endogenous CLDN7 (show CLDN7 Antibodies) promoter in differentiating intestinal epithelial cells and stimulated CLDN7 (show CLDN7 Antibodies) promoter activity.

  9. In conclusion, our data indicate that HNF-4alpha may have a wider role in cell and plasma cholesterol homeostasis by controlling the expression of LXRalpha (show NR1H3 Antibodies) in hepatic cells.

  10. Polymorphisms in ABCG2 (show ABCG2 Antibodies) rs2231142, rs3114020, HNF4alpha rs2071197 and ABCB1 (show ABCB1 Antibodies) rs1128503 were found to be associated with LTG (show TNFSF14 Antibodies) CDR (show RUNX1T1 Antibodies).

Pig (Porcine) Hepatocyte Nuclear Factor 4, alpha (HNF4A) interaction partners

  1. HNF4 positively regulates pUPII gene promoter activity.

Cow (Bovine) Hepatocyte Nuclear Factor 4, alpha (HNF4A) interaction partners

  1. Tetra-primer ARMS-PCR identifies the novel genetic variations of bovine HNF-4alpha gene associating with growth traits.

  2. Results show that chicken ovalbumin upstream promoter transcription factor (show NR2F1 Antibodies) II (COUP-TFII (show NR2F2 Antibodies)), hepatocyte nuclear factor 4alpha (HNF-4alpha) and HNF-4gamma regulate growth hormone receptor (show GHR Antibodies) 1A promoter activity through binding to a common DNA element

HNF4A Antigen Profile

Antigen Summary

The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.

Alternative names and synonyms associated with HNF4A

  • hepatocyte nuclear factor 4, alpha (HNF4A) antibody
  • hepatocyte nuclear factor 4, alpha (hnf4a) antibody
  • Hepatocyte nuclear factor 4 (Hnf4) antibody
  • hepatic nuclear factor 4, alpha (Hnf4a) antibody
  • hepatocyte nuclear factor 4 alpha (LOC100345457) antibody
  • hepatocyte nuclear factor 4, alpha (Hnf4a) antibody
  • CG9310 antibody
  • dHNF-4 antibody
  • dHNF4 antibody
  • Dmel\\CG9310 antibody
  • DmHNF4 antibody
  • fb58h09 antibody
  • Hnf-4 antibody
  • HNF-4(D) antibody
  • HNF-4alpha antibody
  • Hnf-4h antibody
  • hnf4 antibody
  • HNF4A antibody
  • HNF4a7 antibody
  • HNF4a8 antibody
  • HNF4a9 antibody
  • Hnf4alpha antibody
  • id:ibd1279 antibody
  • MODY antibody
  • MODY1 antibody
  • nr2a1 antibody
  • NR2A4 antibody
  • NR2A21 antibody
  • TCF antibody
  • TCF14 antibody
  • wu:fb58h09 antibody

Protein level used designations for HNF4A

hepatocyte nuclear factor 4 alpha , hepatocyte nuclear factor 4, alpha , hepatocyte nuclear factor 4-alpha-like , hepatocyte nuclear factor 4-alpha , CG9310-PA , CG9310-PB , CG9310-PD , CG9310-PE , Hnf4-PA , Hnf4-PB , Hnf4-PD , Hnf4-PE , hepatocyte nuclear factor 4 , hepatocyte nuclear factor 4 homologue , HNF-4-alpha , HNF4 alpha , HNF4alpha10 , HNF4alpha11 , HNF4alpha12 , Nuclear receptor 2A1 , TCF-14 , nuclear receptor subfamily 2 group A member 1 , transcription factor 14 , transcription factor HNF-4 , alpha transcription factor 4 , hepatic nuclear factor 4, alpha , HNF4alpha10/11/12 , hepatic nuclear factor 4 alpha , hepatic nuclear factor 4 , NR2A1 , hepatic nuclear factor 4alpha , nuclear receptor

GENE ID SPECIES
458269 Pan troglodytes
100023834 Monodelphis domestica
100056007 Equus caballus
100402825 Callithrix jacchus
100528306 Ictalurus punctatus
100534656 Ovis aries
100593478 Nomascus leucogenys
44544 Drosophila melanogaster
15378 Mus musculus
100345457 Oryctolagus cuniculus
25735 Rattus norvegicus
3172 Homo sapiens
485884 Canis lupus familiaris
733636 Sus scrofa
509200 Bos taurus
322358 Danio rerio
379762 Xenopus laevis
100713275 Cavia porcellus
419198 Gallus gallus
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