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Details for Product No. ABIN1043810

Interleukin 9 (IL9) antibody (Biotin)

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Antigen
Synonyms P40, HP40, IL-9, Il-9, IL9
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Biotin
Application
»Alternatives Western Blotting (WB), ELISA
Pubmed 3 references available
Catalog no. ABIN1043810
Quantity 100 µg
Price
361.90 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen This purified antibody was prepared from whole rabbit serum produced by repeated immunizations with full length recombinant human IL-9 protein.
Immunogen Type: RecombinantProtein
Isotype IgG
Specificity This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.  This purified antibody has been heated to 56°C for 30 minutes. In ELISA and other immunoreactive assays, this antibody will recognize both native and recombinant human IL-9 in cell supernatants and certain body fluids. A control of similarly diluted normal rabbit IgG is recommended.
Characteristics IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Purification purified
Alternative Name IL-9
Background IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Synonyms: Interleukin-9, IL-9, IL9, T cell growth factor 3, T cell growth factor p40, TCGF 3, Mast cell growth factor, MCGF, Megakaryoblast growth factor, p40 cytokine
Gene ID 3578
NCBI Accession NP_000581.1
UniProt P15248
Research Area Cytokines, Immunology, Virology, Inflammation, Cancer
Application Notes This purified antibody has been tested for use in ELISA and western blotting. By western blot a band approximately 15 kDa in size corresponding to human IL-9 protein is expected in the appropriate cell lysate or extract. Specific conditions for reactivity should be optimized by the end user.
Comment

Gene Name: IL9

Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
Concentration 1.0 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 10 mg/mL Bovine Serum Albumin (BSA) - Immunoglobulin and Protease free
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Store vial at 4° C prior to restoration.   For extended storage aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.  Expiration date is one (1) year from date of opening.
Expiry Date 12 months
Product cited in: Osterfeld, Ahrens, Strait et al.: "Differential roles for the IL-9/IL-9 receptor alpha-chain pathway in systemic and oral antigen-induced anaphylaxis." in: The Journal of allergy and clinical immunology, Vol. 125, Issue 2, pp. 469-476.e2, 2010 (PubMed).

Ciprandi: "Serum interleukin 9 in allergic rhinitis." in: Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, Vol. 104, Issue 2, pp. 180-1, 2010 (PubMed).

Zhu, Liu, Zhao et al.: "Association analysis of polymorphisms in IL-3, IL-4, IL-5, IL-9, and IL-13 with Graves' disease." in: Journal of endocrinological investigation, Vol. 33, Issue 10, pp. 751-5, 2010 (PubMed).

Alternatives for antigen "Interleukin 9 (IL9)", type "Antibodies"
Hosts (67), (6), (2), (1)
Reactivities (52), (23), (13)
Applications (54), (45), (20), (9), (8), (6), (5), (4), (4), (2), (1), (1)
Conjugates (11), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Epitopes (2), (1), (1), (1), (1), (1)
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