IL1RN antibody (AA 26-177) (Biotin)

Catalog No. ABIN1045783

Product Details anti-IL1RN Antibody (Biotin)

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Binding Specificity: AA 26-177

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RN antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Interleukin-1 receptor antagonist protein (26-177AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid freeze and thaw cycles.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for IL1RN

Target: IL1RN (Interleukin 1 Receptor Antagonist (IL1RN))

Alternative Name: IL1RN (IL1RN Products)

Synonyms: DIRA antibody, ICIL-1RA antibody, IL-1RN antibody, IL-1ra antibody, IL-1ra3 antibody, IL1F3 antibody, IL1RA antibody, IRAP antibody, MVCD4 antibody, IRAP1 antibody, IL1RN antibody, IL-1RA antibody, F630041P17Rik antibody, interleukin 1 receptor antagonist antibody, interleukin 1 receptor antagonist-like antibody, IL1RN antibody, Il1rn antibody, IL1RNL antibody

Background:

Background: Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

Aliases: DIRA antibody, F630041P17Rik antibody, ICIL 1RA antibody, ICIL-1RA antibody, ICIL1RA antibody, IL-1ra antibody, IL-1ra3 antibody, IL-1RN antibody, IL1 inhibitor antibody, IL1F3 antibody, IL1RA antibody, IL1RA_HUMAN antibody, IL1RN (IL1F3) antibody, IL1RN antibody, Interleukin 1 receptor antagonist antibody, Interleukin-1 receptor antagonist protein antibody, Intracellular IL 1 receptor antagonist type II antibody, Intracellular interleukin 1 receptor antagonist (icIL 1ra) antibody, IRAP antibody, MGC10430 antibody, MVCD4 antibody, Type II interleukin 1 receptor antagonist antibody

UniProt: P18510

Pathways: NF-kappaB Signaling, Hormone Transport, Cancer Immune Checkpoints