Transglutaminase 2 antibody (AA 578-591)

Catalog No. ABIN1104653

Product Details anti-Transglutaminase 2 Antibody

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Binding Specificity: AA 578-591

Reactivity: Mouse, Rat

Host: Goat

Clonality: Polyclonal

Conjugate: This Transglutaminase 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human TGM2 / Transglutaminase 2. This antibody is expected to recognize isoform a (NP_004604.2) only.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%) Galago, Elephant, Panda, Dog, Bat, Bovine, Horse, Porcine, Guinea pig (93%) Rabbit, Opossum (86%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-ERDLYLENPEIKIR from an internal region of human TGM2 / Transglutaminase 2 (NP_004604.2). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster (100%), Galago, Elephant, Panda, Dog, Bat, Bovine, Horse, Porcine, Guinea pig (93%), Rabbit, Opossum (86%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:8000), WB (1 - 3 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:8000. Western blot: Approx 80kD band observed in Mouse and Rat Kidney lysates (calculated MW of 77.3kD according to Human NP_004604.2 and 77.0kD according to Mouse NP_033399.1). Recommended concentration: 1-3 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Transglutaminase 2

Target: Transglutaminase 2 (TGM2) (Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))

Alternative Name: TGM2 / Transglutaminase 2 (TGM2 Products)

Synonyms: G-ALPHA-h antibody, GNAH antibody, TG2 antibody, TGC antibody, tgm2 antibody, zgc:101081 antibody, TgaseII antibody, TGM2 antibody, fc12b04 antibody, wu:fc12b04 antibody, zgc:136700 antibody, TGL2 antibody, G[a]h antibody, TGase2 antibody, tTG antibody, tTGas antibody, transglutaminase 2 antibody, transglutaminase 2, C polypeptide A antibody, transglutaminase 2b antibody, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antibody, transglutaminase 2, C polypeptide antibody, TGM2 antibody, tgm2a antibody, Tgm2 antibody, tgm2b antibody

Background: Name/Gene ID: TGM2

Synonyms: TGM2, G-ALPHA-h, GNAH, TG(C), Transglutaminase 2, Transglutaminase C, TG2, TGase H, TGase-2, TGase-H, Transglutaminase H, TGase C, TGC, TTG, C polypeptide, Tgase II, Tissue transglutaminase, Transglutaminase-2

Gene ID: 7052

NCBI Accession: NP_004604

UniProt: P21980

Pathways: Tube Formation, Thromboxane A2 Receptor Signaling