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APOB antibody
APOB
Reactivity: Human
EIA, IHC (fro)
Host: Mouse
Monoclonal
2-00E-003
unconjugated
Product Details anti-APOB Antibody
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Target
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APOB
(Apolipoprotein B (APOB))
Reactivity
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Human
Host
All hosts for APOB antibodies
Mouse
Clonality
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Monoclonal
Conjugate
All conjugates for APOB antibodies
This APOB antibody is un-conjugated
Application
All applications for APOB antibodies
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
The antibody reacts with Low Density Lipoproteins of Human plasma. It is specific for fragment T2, the carboxyterminal thrombolytic peptide of Human Apo-B. No crossreactions with other Human plasma proteins were detected.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Sodium sulfate + DEAE-cellulose chromatography, gradient elution
Clone
2-00E-003
Isotype
IgG1
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Discover our top product APOB Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Reconstitution
Restore with 1 mL sterile water
Concentration
0.5 mg/mL (prior to lyophilization)
Buffer
100 mM Sodium Chloride, 10 mM Sodium Phosphate, pH 8.0, 0.1 % (w/v) Mannitol and 1 mM Sodium Azide as preservative
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for APOB
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Target
APOB
(Apolipoprotein B (APOB))
Alternative Name
Apolipoprotein B (Apo B) (APOB Products )
Synonyms
FLDB antibody, LDLCQ4 antibody, Ac1-060 antibody, Apo B-100 antibody, ApoB-100 antibody, ApoB-48 antibody, AI315052 antibody, apob-100 antibody, apob-48 antibody, APOB-100 antibody, ApoB(100) antibody, APOB antibody, apolipoprotein B antibody, APOB antibody, Apob antibody
Background
Apolipoprotein B consists of a single polypeptide chain with a molecular weight of 516 kDa and is mostly synthesised in the liver. It is a major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL) as well as being a major component of lipoprotein (a). Apolipoprotein B is a ligand for the LDL receptor and elevated levels are associated with premature atherosclerosis. Normal plasma apolipoprotein B levels are around 800 mg/L.Synonyms: Apo-B, ApoB, ApoB-100, ApoB100
Gene ID
338
NCBI Accession
NP_000375
UniProt
P04114
Pathways
Lipid Metabolism
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