N-Cadherin antibody (Middle Region)
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- Target See all N-Cadherin (CDH2) Antibodies
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
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Binding Specificity
- AA 701-714, Middle Region
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This N-Cadherin antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects Cadherin-2 (701-714). No cross reactivity with other proteins.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, rat
- Purification
- Immunogen affinity purified
- Immunogen
- Synthetic peptide corresponding to a sequence at the middle region of human N-Cadherin (701-714aa) .Remarks: Sequence is identical to the rat sequence.
- Isotype
- IgG
- Top Product
- Discover our top product CDH2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Reconstitution
- 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3
- Preservative
- Sodium azide, Thimerosal (Merthiolate)
- Precaution of Use
- This product contains Sodium azide and Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- Alternative Name
- Cadherin-2 (CDH2 Products)
- Synonyms
- CD325 antibody, CDHN antibody, CDw325 antibody, NCAD antibody, N-cadherin antibody, cadherin-2 antibody, cdhn antibody, ncad antibody, cdw325 antibody, CDH2 antibody, Cadherin-2 antibody, Ncad antibody, glo antibody, lyr antibody, pac antibody, wu:fb47h04 antibody, cadherin 2 antibody, cadherin 2 S homeolog antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, CDH2 antibody, cdh2.S antibody, cdh2 antibody, Cdh2 antibody
- Background
- N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-,and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96 % identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11.2. Cadherin regulates dendritic spine morphogenesisSynonyms: CDH2, CDHN, CDw325, Cadherin N, N-Cadherin, NCAD, Neural cadherin
- Gene ID
- 83501
- NCBI Accession
- NP_112623
- UniProt
- Q9Z1Y3
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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