GJB1 antibody (AA 105-123)

Catalog No. ABIN1107368

Product Details anti-GJB1 Antibody

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Binding Specificity: AA 105-123

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GJB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: This antibody reacts to GJB1 / Cx32.

Purification: Affinity chromatography

Immunogen: Synthetic connexin-32 peptide (amino acids 105-123) conjugated to KLH.

Clone: CXN-32

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1.2 % sodium acetate or neutral PBS

Concentration: 0,1 mg/mL

Buffer: 1.2 % sodium acetate, with 2 mg BSA and 0.01 mg sodium azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Prior to reconstitution store at -20 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GJB1

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Alternative Name: GJB1 / Cx32 (GJB1 Products)

Synonyms: GJIC antibody, cmtx antibody, cmtx1 antibody, connexin-30 antibody, connexin32 antibody, cx30 antibody, cx32 antibody, gja1 antibody, CX32 antibody, GJB1 antibody, AI118175 antibody, Cnx32 antibody, Cx32 antibody, Gjb-1 antibody, CMTX antibody, CMTX1 antibody, gjb1-a antibody, gap junction protein beta 1 antibody, connexin 32 antibody, probable serine/threonine-protein kinase CST antibody, gap junction protein, beta 1 antibody, gap junction protein beta 1 L homeolog antibody, gjb1 antibody, CX32 antibody, LOC9303136 antibody, GJB1 antibody, Gjb1 antibody, gjb1.L antibody

Background: Connexin32(CX32), also known as GAP junction protein beta-1(GJB1). Connexins are membrane-spanning proteins that assemble to form gap junction channels that facilitate the transfer of ions and small molecules between cells. CX32 expressed in liver and peripheral nerve. CX32 gene is mapped to Xp11-q13 and is directly regulated by the transcription factor SOX10.Synonyms: Connexin-32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein

Gene ID: 2705

NCBI Accession: NP_000157

UniProt: P08034

Pathways: Cell-Cell Junction Organization