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IFNA2 antibody
IFNA2
Reactivity: Human
WB, EIA, Func, Neut
Host: Mouse
Monoclonal
N27
unconjugated
Product Details anti-IFNA2 Antibody
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Target
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IFNA2
(Interferon, alpha 2 (IFNA2))
Reactivity
All reactivities for IFNA2 antibodies
Human
Host
All hosts for IFNA2 antibodies
Mouse
Clonality
All clonalities for IFNA2 antibodies
Monoclonal
Conjugate
All conjugates for IFNA2 antibodies
This IFNA2 antibody is un-conjugated
Application
All applications for IFNA2 antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func), Neutralization (Neut)
Specificity
N27 is specific for INFalpha(II) and does not crossreact with INFalpha(I).
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Purified
Immunogen
A BALB/c mouse was immunized with E-coli derived, purified recombinant IFN-alpha 2c and spleen cells were fused with mouse myeloma cells NS1.
Clone
N27
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0,1 mg/mL
Buffer
PBS, 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target Details for IFNA2
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Target
IFNA2
(Interferon, alpha 2 (IFNA2))
Alternative Name
IFNA2 / Interferon alpha-2 (IFNA2 Products )
Synonyms
IFN-alphaA antibody, IFNA antibody, IFNA2B antibody, INFA2 antibody, Ifa2 antibody, IFNA2 antibody, interferon alpha 2 antibody, interferon, alpha 2 antibody, interferon-alpha-2 antibody, interferon alpha-2 antibody, IFNA2 antibody, Ifna2 antibody, ifna2 antibody, IFN-ALPHA2 antibody, LOC102142148 antibody
Background
The alpha interferons are involved in virus resistance in target cells for these viruses. They are known to block cell proliferation and to regulate MHC class I antigen expression. The IFNalpha family has pseudogenes in two families (I and II), one with a mature length of 166aa and one of 172aa. Cells producing IFNalpha are lymphocytes, monocytes, macrophages and cell lines such as Namalwa and KGI. Bioassays for IFNalpha include cytopathic effect blocking, by viruses such as VSV, SFV and BMCV, on their target cells. A number of receptors for IFNalpha are now known and seem to be expressed on most cell types.Synonyms: IFN-alpha 2, Interferon alpha-A, LeIF A
Gene ID
3440
NCBI Accession
NP_000596
UniProt
P01563
Pathways
JAK-STAT Signaling , Regulation of Leukocyte Mediated Immunity , Production of Molecular Mediator of Immune Response , Hepatitis C
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