PRMT3 antibody (Internal Region)

Catalog No. ABIN1108735

Product Details anti-PRMT3 Antibody

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Binding Specificity: AA 468-421, Internal Region

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This PRMT3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Sequence: DPKTLISEPC GIKH

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein A

Immunogen: Peptide with sequence from the internal region of Human PRMT3 (NP_005779.1, NP_001138638.1, NP_001138639.1). Genename: PRMT3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PRMT3

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Alternative Name: PRMT3 (PRMT3 Products)

Synonyms: HRMT1L3 antibody, 2010005E20Rik antibody, 2410018A17Rik antibody, AL033309 antibody, Hrmt1l3 antibody, PRMT3 antibody, hrmt1l3 antibody, zgc:112498 antibody, ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 3 antibody, ATPRMT3 antibody, protein arginine methyltransferase 3 antibody, protein arginine methyltransferase 3 antibody, protein arginine N-methyltransferase 3 antibody, protein arginine methyltransferase 3 S homeolog antibody, PRMT3 antibody, Prmt3 antibody, prmt3 antibody, prmt3.S antibody

Background: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.Synonyms: HRMT1L3, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein, Protein arginine N-methyltransferase 3

Gene ID: 10196

NCBI Accession: NP_005779

Pathways: Protein targeting to Nucleus