anti-Thrombopoietin antibody (THPO)

Details for Product anti-THPO Antibody No. ABIN1109245
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Synonyms tpo, LOC100231762, TPO, MGDF, MKCSF, ML, MPLLG, THCYT1, Mgdf, Ml, Mpllg, Tpo, Tpo1, Tpo2, Tpo3, Tpo4
(121), (51), (17), (2), (1), (1), (1), (1)
(84), (31), (28), (21)
Clonality (Clone)
Monoclonal ()
This Thrombopoietin antibody is un-conjugated
(14), (8), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(116), (101), (16), (15), (14), (10), (10), (9), (6), (6), (5), (4), (3), (2), (2), (2), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Clone 1B11
Isotype IgG2a
Specificity Recognizes Thrombopoietin (THPO).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Purified
Alternative Name Thrombopoietin (THPO Antibody Abstract)
Background Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Alternate splicing results in multiple transcript variants of this gene.Synonyms: C-mpl ligand, MGDF, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, Myeloproliferative leukemia virus oncogene ligand, THPO
Molecular Weight 37.8 kDa
Gene ID 7066
Research Area Cancer, Cell Cycle, Hormones
Pathways JAK-STAT Signaling
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer 0.05 % Sodium Azide 0.5 % protein stabilizer
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
ELISA image for anti-Thrombopoietin antibody (THPO) (ABIN1109245) anti-Thrombopoietin (THPO) antibody
Flow Cytometry (FACS) image for anti-Thrombopoietin antibody (THPO) (ABIN1109245) anti-Thrombopoietin (THPO) antibody (Image 2)
Western Blotting (WB) image for anti-Thrombopoietin antibody (THPO) (ABIN1109245) anti-Thrombopoietin (THPO) antibody (Image 3)
Background publications Graziano, Carone, Panza et al.: "Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation." in: Blood, Vol. 114, Issue 8, pp. 1655-7, 2009 (PubMed).

Eissa, Gad, Rabie et al.: "Thrombopoietin level in patients with chronic liver diseases." in: Annals of hepatology, Vol. 7, Issue 3, pp. 235-44, 2008 (PubMed).

Catalog No. ABIN1109245
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