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TMPRSS3 antibody

TMPRSS3 Reactivity: Human WB, EIA, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1109275
  • Target See all TMPRSS3 Antibodies
    TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
    Reactivity
    • 34
    • 18
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 31
    • 2
    • 1
    Rabbit
    Clonality
    • 32
    • 2
    Polyclonal
    Conjugate
    • 22
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TMPRSS3 antibody is un-conjugated
    Application
    • 27
    • 16
    • 11
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    This antibody reacts with 49 kDa TMPRSS3 protein.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Antigen Affinity Chromatography
    Immunogen
    A 15 residue synthetic peptide derived from specific domain of Human TMPRSS3 protein
    Top Product
    Discover our top product TMPRSS3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    0.1 M Tris, 0.1 M Glycine, 50 % Glycerol ( pH 7.8), 0.02 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store antibody (in aliquots) at -20 °C.
  • Target
    TMPRSS3 (Transmembrane Protease, Serine 3 (TMPRSS3))
    Alternative Name
    TMPRSS3 (TMPRSS3 Products)
    Synonyms
    TMPRSS3 antibody, DKFZp469L1528 antibody, DFNB10 antibody, DFNB8 antibody, ECHOS1 antibody, TADG12 antibody, transmembrane protease, serine 3 antibody, TMPRSS3 antibody, Tmprss3 antibody
    Background
    TMPRSS3 is a 437 amno acid membrane bound serine protease and a member of the S1 peptidase family. TMPRSS3 contains an amino-terminal signalanchor sequence and a glycosylated extracellular region containing the serine protease domain. Two novel missense mutations of TMPRSS3, W251C and P404L, alter the highly conserved amino acids of the serine protease domain. TMPRSS3 is expressed in many tissues, including fetal cochle,a a subset of pancreatic cancer and various other cancer tissues. TMPRSS3 is also overexpressed in cancer, suggesting that it may be important for processes in metastasis formation and tumor invasion.Synonyms: ECHOS1, TADG-12, TADG12, Transmembrane protease serine 3, Tumor-associated differentially-expressed gene 12 protein
    Gene ID
    64699
    NCBI Accession
    NP_076927
    Pathways
    Sensory Perception of Sound
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