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Transglutaminase 2 antibody
TGM2
Reactivity: Human, Guinea Pig
WB, IHC (fro), EIA
Host: Mouse
Monoclonal
7D2
unconjugated
Product Details anti-Transglutaminase 2 Antibody
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Target
See all Transglutaminase 2 (TGM2) Antibodies
Transglutaminase 2 (TGM2)
(Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
Reactivity
All reactivities for Transglutaminase 2 antibodies
Human, Guinea Pig
Host
All hosts for Transglutaminase 2 antibodies
Mouse
Clonality
All clonalities for Transglutaminase 2 antibodies
Monoclonal
Conjugate
All conjugates for Transglutaminase 2 antibodies
This Transglutaminase 2 antibody is un-conjugated
Application
All applications for Transglutaminase 2 antibodies
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
Cross-Reactivity (Details)
Species reactivity (tested):Human, Guinea Pig.
Purification
Affinity Chromatography on Protein A
Clone
7D2
Isotype
IgG3
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Discover our top product TGM2 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Reconstitution
Restore in distilled water.
Buffer
0.1 M Tris, 0.1 M Glycine and 2 % Sucrose, None
References for anti-Transglutaminase 2 antibody (ABIN1109303)
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Maffei, Laverrière, Wu, Triboulet, Perrinet, Duchateau, Matondo, Hollis, Gourley, Rupp, Keillor, Subtil : "Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells. " in: The EMBO journal , Vol. 39 , Issue 8 , pp. e102166 , (2020 ) (PubMed ).
Target Details for Transglutaminase 2
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Target
Transglutaminase 2 (TGM2)
(Transglutaminase 2 (C Polypeptide, Protein-Glutamine-gamma-Glutamyltransferase) (TGM2))
Alternative Name
Transglutaminase-2 (TGM2 Products )
Synonyms
G-ALPHA-h antibody, GNAH antibody, TG2 antibody, TGC antibody, tgm2 antibody, zgc:101081 antibody, TgaseII antibody, TGM2 antibody, fc12b04 antibody, wu:fc12b04 antibody, zgc:136700 antibody, TGL2 antibody, G[a]h antibody, TGase2 antibody, tTG antibody, tTGas antibody, transglutaminase 2 antibody, transglutaminase 2, C polypeptide A antibody, transglutaminase 2b antibody, transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) antibody, transglutaminase 2, C polypeptide antibody, TGM2 antibody, tgm2a antibody, Tgm2 antibody, tgm2b antibody
Background
Transglutaminase II catalyzes calcium-dependent post-translational modification of proteins by formation of an isopeptide bond within or between polypeptide chains. It is also known as TGC, tTG, type II-, Gh, cytosolic-, liver-, endothelial-, erythrocyte-, cellular-transglutaminase. Different tissues and cell types express varying amounts of tissue transglutaminase with a markedly hugh expression in rheumatoid lesions. It is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Pathways
Tube Formation , Thromboxane A2 Receptor Signaling
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