This Cardiac Troponin T2 antibody is un-conjugated
Application
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
This antibody is specific for Cardiac Troponin T and does not react with the Skeletal form. The epitope has been mapped to a region between amino acids 60-71 of the native protein.
No Cross-Reactivity
Fish, Rat (Rattus), Goat, Dog (Canine), Pig (Porcine), Mouse (Murine), Cat (Feline), Rabbit
Cardiac Troponin T, a 36 kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.Synonyms: TNNT2, TnTc, cTnT