GDF2 antibody (AA 87-98)

Catalog No. ABIN114066

Product Details anti-GDF2 Antibody

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Binding Specificity: AA 87-98

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF2 antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Sequence: CKDDMGVPTL KYH

Specificity: This antibody detects BMP-9.

Purification: Affinity chromatography on Protein G

Immunogen: Synthetic peptide corresponding to the amino acids 87 - 98 of the native molecule conjugated to keyhole limpet haemocyanin.

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 5.0 mg/mL

Buffer: Phosphate buffered saline, pH 7.2, containing 0.09 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing. Dilute only prior to immediate use

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody (undiluted) at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GDF2

Target: GDF2 (Growth Differentiation Factor 2 (GDF2))

Alternative Name: BMP9 (GDF2 Products)

Synonyms: bmp9 antibody, BMP-9 antibody, BMP9 antibody, Bmp9 antibody, DSL1 antibody, growth differentiation factor 2 antibody, gdf2 antibody, GDF2 antibody, Gdf2 antibody

Background: BMP9 is a member of the TGF-beta superfamily. BMPs act through binding with a receptor complex consisting of type I and type II serine/threonine kinases, resulting ultimately in the activation of the Smad protein and mitogen-activated protein kinase (MAPK) signaling pathways. Several antagonist proteins, including, noggin, chordin, gremlin and follistatin, are responsible for modulating the signaling effects of BMPs, through the binding and blocking of receptor ligands, thereby preventing activation.Synonyms: GDF-2, GDF2, Growth/differentiation factor 2

Gene ID: 2658

NCBI Accession: NP_057288

UniProt: Q9UK05

Pathways: Transition Metal Ion Homeostasis