BMP10 antibody (AA 86-96)
-
- Target See all BMP10 Antibodies
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
-
Binding Specificity
- AA 86-96
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This BMP10 antibody is un-conjugated
-
Application
- Enzyme Immunoassay (EIA)
- Specificity
- Bone Morphogenetic Protein 10 (BMP-10) 86-96.
- Purification
- Ammonium sulphate fractionation
- Immunogen
- KLH conjugate, sequence: C-L-D-K-G-V-V-T-Y-K-F-K
- Top Product
- Discover our top product BMP10 Primary Antibody
-
-
- Application Notes
-
Peptide-ELISA: 1/50 - 1/200. In a simple ELISA using 1 g of antigen coated per well, the50 % OD was observed at an antibody dilution of 1/100. With 1 g of peptide-BSA coatedper well the 50 % OD was observed at 1/2500. Under the same conditions the end pointwas observed at 1/80K. Competitive ELISA: pep-BSA plates, coated at 1 g/well, antibodydiluted 1/10K. Pep-BSA displaces in the range 0.1 to 100 μg/mL. The free peptide does notdisplace in this assay system.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.8 mg/mL (OD280)
- Buffer
- PBS, pH 7.2, with 0.09 % sodium azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- BMP10 (Bone Morphogenetic Protein 10 (BMP10))
- Alternative Name
- BMP10 (BMP10 Products)
- Synonyms
- BMP10 antibody, si:dkey-13n15.5 antibody, Bmp10 antibody, BMP9 antibody, BMP-10 antibody, bone morphogenetic protein 10 antibody, BMP10 antibody, bmp10 antibody, LOC662386 antibody, Bmp10 antibody
- Background
- Bone morphogenetic protein-10 (BMP10) belongs to the transforming growth factor beta (TGFß) family. BMPs, named for their initial biological activity of inducing ectopic bone formation, have been linked to multiple steps of cardiac development. BMP10 is translated as a precursor protein (preproprotein) with N-terminal hydrophobic leader peptide followed by prodomain and the mature C-terminal region that is released after the cleavage at multibasic motif RXRR. Data strongly suggest that BMP10 is an essential component in modulating cardiomyocyte proliferation and maturation during cardiac ventricular development.Synonyms: BMP-10, Bone morphogenetic protein 10
- Gene ID
- 27302
- NCBI Accession
- NP_055297
- UniProt
- O95393
- Pathways
- Hormone Activity, Regulation of Muscle Cell Differentiation
-