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Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) antibody
| Antigen | Actin, alpha 2, Smooth Muscle, Aorta (ACTA2) |
| Synonyms |
AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, ...
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| Clonality | Monoclonal (1A4-asm-1) |
| Host |
 Alternatives Mouse |
| Reactivity |
Alternatives Cow (Bovine), Chicken, Human, Mouse (Murine), Rabbit, Rat (Rattus) |
| Application |
Alternatives Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|
| Catalog no. | ABIN114404 |
| Quantity | 1 ml (Variants) |
| Price | 350.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | Synonyms: Alpha-actin-2, ACTVS, GIG46, Cell growth-inhibiting gene 46 protein |
| Alternative name | Aortic smooth muscle Actin / ACTA2 |
| Swiss-Prot | P62736 |
| Immunogen | N-terminal decapeptide of alpha-smooth muscle actin |
| Isotype | IgG2a (Matching secondary antibodies) |
| Clone | 1A4-asm-1 |
| Description | Smooth muscle actin is expressed in normal smooth muscle and in myoepithelial cells,and also in tumours derived from these cells. Actins are involved in maintaining thestructure and integrity of a cell, as well as cell motility. They are highly conserved proteinsand make up the majority of the contractile apparatus. To date, six different actin isoformshave been described. |
| Specificity | This antibody is specific to alpha-smooth isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. The antibody does not cross-react with beta and gamma-cytoplasmic, alpha-sarcomericand alpha-myocardial actin isoforms. Cellular Localization: Cytoplasmic. Species: Bovine, Chicken, Human, Mouse, Rabbit and Rat. Others not tested. |
| Synonyms | AAT6, ACTSA, Actvs, a-SMA, SMalphaA, 0610041G09Rik, wu:fb63d03, MGC78870, ACTA2, actc1, actsa, MGC89192, MGC127800, ACT-4, DKFZp469E0314, Acta2, asma, acta, cftd, mpfd, nem1, nem2, nem3, acta2, cftd1, cftdm, MGC52636, MGC79039 |
Application Details
| Application Notes | Immunohistochemistry on Formalin Fixed Paraffin Embedded Sections: Use Actin antibodyat 1/25-1/50 dilution in an ABC method for 30 minutes at room temperature. Recommended Positive Control: Leiomyoma. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. |
| Storage | Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch. |
| Research Area | Extracellular Matrix, Cell/Tissue Markers |
| Restrictions | For Research Use only |
Images
| Formalin fixed paraffin embedded human leiomyoma stained with Smooth Muscle Actin antibody ABIN114404/ABIN114404-05 |
Alternatives
Alternatives for antigen "Actin, alpha 2, Smooth Muscle, Aorta (ACTA2)", type "Antibodies"
| Hosts | Mouse (37), Rabbit (10), Goat (4) |
| Reactivities | Human (39), Rat (Rattus) (18), Mouse (Murine) (17), Chicken (16), Cow (Bovine) (14), Rabbit (13), Baboon (3), Dog (Canine) (2), Monkey (2), Vertebrates (2) |
| Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (41), Immunofluorescence (IF) (17), Western Blotting (WB) (16), Immunohistochemistry (Frozen Sections) (IHC (fro)) (11), Enzyme Immunoassay (EIA) (7), ELISA (5), Immunohistochemistry (IHC) (5), ELISA (Detection) (1), Flow Cytometry (FACS) (1), Immunoprecipitation (IP) (1) |
| Conjugates | Biotin (3) |
| Epitopes | N-Term (5), Ab-1 (2) |
