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Smooth Muscle Actin antibody

ACTA2 Reactivity: Human, Rat, Mouse, Monkey WB, IHC, FACS, ELISA, ICC Host: Mouse Monoclonal 4A4 unconjugated
Catalog No. ABIN968947
  • Target See all Smooth Muscle Actin (ACTA2) Antibodies
    Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
    Reactivity
    • 124
    • 84
    • 77
    • 31
    • 27
    • 25
    • 21
    • 15
    • 14
    • 14
    • 13
    • 13
    • 13
    • 13
    • 10
    • 7
    • 2
    • 1
    Human, Rat, Mouse, Monkey
    Host
    • 69
    • 55
    • 1
    Mouse
    Clonality
    • 79
    • 46
    Monoclonal
    Conjugate
    • 66
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Smooth Muscle Actin antibody is un-conjugated
    Application
    • 70
    • 53
    • 38
    • 38
    • 27
    • 26
    • 18
    • 14
    • 10
    • 7
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Immunogen
    Synthesized peptide of human ACTA2.
    Clone
    4A4
    Isotype
    IgG1
    Top Product
    Discover our top product ACTA2 Primary Antibody
  • Application Notes
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    4°C, -20°C for long term storage
  • Shimojima, Yamamoto: "ACTA2 is not a major disease-causing gene for moyamoya disease." in: Journal of human genetics, Vol. 54, Issue 11, pp. 687-8, (2009) (PubMed).

    Morisaki, Akutsu, Ogino, Kondo, Yamanaka, Tsutsumi, Yoshimuta, Okajima, Matsuda, Minatoya, Sasaki, Tanaka, Ishibashi-Ueda, Morisaki: "Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD)." in: Human mutation, Vol. 30, Issue 10, pp. 1406-11, (2009) (PubMed).

  • Target
    Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
    Alternative Name
    ACTA2 (ACTA2 Products)
    Synonyms
    AAT6 antibody, ACTSA antibody, MYMY5 antibody, GAMMA-ACTIN antibody, ACT antibody, ACTA3 antibody, ACTE antibody, ACTL3 antibody, ACTSG antibody, Act-4 antibody, Act4 antibody, SMGA antibody, 0610041G09Rik antibody, Actvs antibody, SMalphaA antibody, a-SMA antibody, alphaSMA antibody, wu:fb63d03 antibody, ASMA antibody, SMactin antibody, a-sma antibody, aat6 antibody, actsa antibody, mymy5 antibody, sm-actin antibody, ACTA2 antibody, actc1 antibody, ACT-4 antibody, asma antibody, ACTGE antibody, actin, alpha 2, smooth muscle, aorta antibody, actin, gamma 2, smooth muscle, enteric antibody, actin, alpha 2, smooth muscle, aorta L homeolog antibody, ACTA2 antibody, ACTG2 antibody, Actg2 antibody, Acta2 antibody, acta2 antibody, acta2.L antibody
    Background

    Description: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

    Aliases: AAT6, ACTSA, α-Smooth Muscle Actin

    Molecular Weight
    42 kDa
    Gene ID
    59
    HGNC
    59
    Pathways
    Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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