HHV8 antibody

Catalog No. ABIN115219

This Rat Monoclonal antibody specifically detects HHV8 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for HHV8 antibody (ABIN115219)

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This HHV8 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: LN53

Product Details anti-HHV8 Antibody

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogen: Recombinant protein corresponding to the latent nuclear antigen-1 molecule of HHV8.

Isotype: IgG2c

Application Details

Application Notes: Immunohistochemistry: Use at 1/25-1/50 dilution in an ABC method (30 to 60 minutes atroom temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Kaposi's sarcoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for HHV8

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Alternative Name: Herpes Virus Type 8 / HHV8

Target Type: Virus

Background: HHV8 has been found to be associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.Synonyms: HHV-8, KHSV