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HHV8 antibody

HHV8 Reactivity: Human WB, IP Host: Sheep Polyclonal unconjugated
Catalog No. ABIN264910
  • Target See all HHV8 products
    HHV8 (Herpes Virus Type 8 (HHV8))
    Reactivity
    • 3
    • 2
    • 1
    Human
    Host
    • 2
    • 2
    • 1
    • 1
    Sheep
    Clonality
    • 4
    • 2
    Polyclonal
    Conjugate
    • 6
    This HHV8 antibody is un-conjugated
    Application
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Specificity
    Cyclin
    Purification
    Ammonium Sulfate Precipitation
    Immunogen
    Inclusion Bodies from E. Coli expressing his-tagged full length Human cyclin G2 protein.
    Isotype
    IgG
  • Application Notes
    Immunoblotting: 1 - 5 μg/mL. Immunoprecipitation: 10 - 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS, 0.08 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Anderton, Yee, Smith, Crook, White, Allday: "Two Epstein-Barr virus (EBV) oncoproteins cooperate to repress expression of the proapoptotic tumour-suppressor Bim: clues to the pathogenesis of Burkitt's lymphoma." in: Oncogene, Vol. 27, Issue 4, pp. 421-33, (2008) (PubMed).

    Sugaya, Watanabe, Yang, Starost, Kobayashi, Atkins, Borris, Hanan, Schimel, Bryant, Roberts, Skobe, Staskus, Kaldis, Blauvelt: "Lymphatic dysfunction in transgenic mice expressing KSHV k-cyclin under the control of the VEGFR-3 promoter." in: Blood, Vol. 105, Issue 6, pp. 2356-63, (2005) (PubMed).

    Järviluoma, Koopal, Räsänen, Mäkelä, Ojala: "KSHV viral cyclin binds to p27KIP1 in primary effusion lymphomas." in: Blood, Vol. 104, Issue 10, pp. 3349-54, (2004) (PubMed).

  • Target
    HHV8 (Herpes Virus Type 8 (HHV8))
    Alternative Name
    Herpes Virus Type 8 / HHV8 (HHV8 Products)
    Target Type
    Virus
    Background
    Human herpervirus-8 (HHV-8) cyclin is a component of the HHV-8 virus particle. HHV8 has been found to be associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.Synonyms: HHV-8, KHSV
    Molecular Weight
    28.1 kDa
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