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HHV8 antibody

HHV8 Reactivity: Herpes Simplex Virus (HSV) ELISA, IHC, Coat, IF, StM Host: Rat Monoclonal LN53 unconjugated
Catalog No. ABIN6937460
  • Target See all HHV8 products
    HHV8 (Herpes Virus Type 8 (HHV8))
    Reactivity
    • 4
    • 1
    • 1
    Herpes Simplex Virus (HSV)
    Host
    • 2
    • 2
    • 1
    • 1
    Rat
    Clonality
    • 3
    • 3
    Monoclonal
    Conjugate
    • 6
    This HHV8 antibody is un-conjugated
    Application
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunofluorescence (IF), Staining Methods (StM)
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8
    Clone
    LN53
    Isotype
    IgG2c kappa
  • Application Notes

    Positive Control: Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.

    Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Buffer
    10 mM PBS without BSA and without Azide.
    Preservative
    Azide free
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
    Expiry Date
    24 months
  • Target
    HHV8 (Herpes Virus Type 8 (HHV8))
    Alternative Name
    Human Herpes Virus 8 (HHV8) (HHV8 Products)
    Target Type
    Virus
    Background
    HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients, kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.
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