HHV8 antibody

Catalog No. ABIN6937460

This Rat Monoclonal antibody specifically detects HHV8 in IHC, ELISA and IF. It exhibits reactivity toward Various Species.

Quick Overview for HHV8 antibody (ABIN6937460)

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Reactivity: Various Species

Host: Rat

Clonality: Monoclonal

Conjugate: This HHV8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: LN53

Product Details anti-HHV8 Antibody

Purpose: Human Herpes Virus 8 (HHV8) Antibody

Specificity: HHV 8 encodes a latent nuclear antigen (LNA), which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product, which may be related to its oncogenic activity. HHV8 is associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. HHV 8 is the likely etiological agent of Kaposis sarcoma.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant protein corresponding to the latent nuclear antigen 1 molecule of HHV8

Isotype: IgG2c, kappa

Application Details

Application Notes:

Positive Control: Herpes simplex type 1 (HSV-1) extract or infected cells. Tissue.

Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for HHV8

Target: HHV8 (Herpes Virus Type 8 (HHV8))

Alternative Name: Human Herpes Virus 8 (HHV8)

Target Type: Virus

Background:

HHV8; Human Herpes Virus 8; Human herpesvirus 8; Kaposi's sarcoma associated herpes virus; KSHV

Kaposi's sarcoma. Cultured cells infected with HHV8.