DcR1 antibody
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- Target See all DcR1 (TNFRSF10C) Antibodies
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This DcR1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Specificity
- Recognizes human TRAIL-R3.
- Cross-Reactivity
- Human
- Cross-Reactivity (Details)
- Does not cross-react with human TRAIL-R1, -R2 or -R4.
- Purification
- Purified from concentrated hybridoma tissue culture supernatant.
- Purity
- >95 % (SDS-PAGE)
- Immunogen
- Recombinant human TRAIL-R3 (DcR1).
- Clone
- TR3-06
- Isotype
- IgG1
- Top Product
- Discover our top product TNFRSF10C Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Specially developed for the immunohistochemical detection of TRAIL-R3 in paraffin embedded tissue. Has been shown to detect TRAIL-R3 expressed at endogenous levels in paraffin-embedded tissue in different mammary carcinoma tissues.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Expiry Date
- 12 months
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- Target
- DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))
- Alternative Name
- TRAIL-R3 (TNFRSF10C Products)
- Synonyms
- CD263 antibody, DCR1 antibody, DCR1-TNFR antibody, LIT antibody, TRAIL-R3 antibody, TRAILR3 antibody, TRID antibody, TNFRSF10C antibody, TNF receptor superfamily member 10c antibody, TNFRSF10C antibody
- Background
- TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL mediated apoptosis by competing with TRAIL-R1 and R2 for binding to the ligand.
- UniProt
- O14798
- Pathways
- Apoptosis
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