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CD35 antibody (FITC)
CR1
Reactivity: Human, Monkey
FACS
Host: Mouse
Monoclonal
E11
FITC
Product Details anti-CD35 Antibody (FITC)
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Target
See all CD35 (CR1) Antibodies
CD35 (CR1)
(Complement Component Receptor 1 (CD35) (CR1))
Reactivity
All reactivities for CD35 antibodies
Human, Monkey
Host
All hosts for CD35 antibodies
Mouse
Clonality
All clonalities for CD35 antibodies
Monoclonal
Conjugate
All conjugates for CD35 antibodies
This CD35 antibody is conjugated to FITC
Application
All applications for CD35 antibodies
Flow Cytometry (FACS)
Purification
Ion Exchange Chromatography.
Immunogen
Human acute monocytic leukaemia cells. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.
Clone
E11
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Flow Cytometry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
0.1 mg/mL
Buffer
PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing. This product is photosensitive and should be protected from light
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for CD35
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Target
CD35 (CR1)
(Complement Component Receptor 1 (CD35) (CR1))
Alternative Name
CD35 / C3BR (CR1 Products )
Synonyms
C3BR antibody, C4BR antibody, CD35 antibody, KN antibody, C3DR antibody, CD21 antibody, Cr-1 antibody, Cr-2 antibody, Cr1 antibody, CR1-L antibody, CR2 antibody, CR1 antibody, complement C3b/C4b receptor 1 (Knops blood group) antibody, complement receptor 2 antibody, complement component (3d/Epstein Barr virus) receptor 2 antibody, complement receptor type 1 antibody, CR1 antibody, Cr2 antibody, CR2 antibody, LOC718120 antibody
Background
CD35 is a single chain cell surface glycoprotein which exists in four allotypic forms (A,B,C,D) of 190kD, 220kD, 160kD and 250kD respectively. The molecule is expressed by granulocytes, monocytes, B cells and some T cells. Functionally CD35 acts as a receptor for the C3b component of complement.Synonyms: C3b/C4b receptor, CR1, Complement receptor type 1
Gene ID
9606
UniProt
P17927
Pathways
Complement System , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Endopeptidase Activity
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