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Integrin Alpha2b (CD41) antibody

Details for Product No. ABIN118659, Supplier: Log in to see
Antigen
  • AI172977
  • CD41
  • CD41B
  • GpIIb
  • alphaIIb
  • BDPLT16
  • BDPLT2
  • GP2B
  • GPIIb
  • GT
  • GTA
  • HPA3
  • integrin alpha 2b
  • integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
  • Itga2b
  • ITGA2B
Reactivity
Human
387
150
27
25
21
18
17
12
7
5
1
1
1
1
Host
Mouse
351
117
58
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
66
54
40
13
11
10
9
8
7
7
7
6
6
6
5
5
5
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
407
89
84
78
54
53
48
27
20
14
13
8
7
6
5
3
2
2
2
2
2
1
1
1
1
1
Options
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Immunogen Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Clone PM6-248
Isotype IgG1
Purification Affinity Chromatography on Protein G.
Alternative Name CD41 / ITGA2B (CD41 Antibody Abstract)
Background CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
Gene ID 9606
UniProt P08514
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Michelson, Page, Casey, Trucksess, Love, Milstien, Wilson, Massaquoi, Crofford, Hallett: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Hornby, Brown, Wilkinson, Mattock, Authi: "Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa." in: British journal of haematology, Vol. 79, Issue 2, pp. 277-85, 1992 (PubMed).