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Integrin Alpha2b (CD41) antibody

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Antigen
  • AI172977
  • alphaIIb
  • BDPLT2
  • BDPLT16
  • CD41
  • CD41B
  • GP2B
  • GPIIb
  • GpIIb
  • GT
  • GTA
  • HPA3
Reactivity
Human
378
146
23
20
19
18
15
7
4
4
1
1
1
Host
Mouse
344
117
57
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
65
53
39
12
10
10
9
8
7
7
5
5
5
5
5
5
5
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS)
395
93
77
71
71
56
45
42
22
13
12
7
6
3
2
2
2
2
2
1
1
1
1
1
Supplier
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Immunogen Human platelet plasma membrane. Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
Clone PM6-248
Isotype IgG1
Purification Affinity Chromatography on Protein G.
Alternative Name CD41 / ITGA2B (CD41 Antibody Abstract)
Background CD41 is a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
Gene ID 9606
UniProt P08514
Application Notes Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Background publications Michelson, Page, Casey, Trucksess, Love, Milstien, Wilson, Massaquoi, Crofford, Hallett: "An eosinophilia-myalgia syndrome related disorder associated with exposure to L-5-hydroxytryptophan." in: The Journal of rheumatology, Vol. 21, Issue 12, pp. 2261-5, 1995 (PubMed).

Hornby, Brown, Wilkinson, Mattock, Authi: "Activation of human platelets by exposure to a monoclonal antibody, PM6/248, to glycoprotein IIb-IIIa." in: British journal of haematology, Vol. 79, Issue 2, pp. 277-85, 1992 (PubMed).