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Integrin Alpha2b antibody

CD41 Reactivity: Human, Primate FACS, IHC (fro) Host: Mouse Monoclonal HIP8 unconjugated
Catalog No. ABIN120752
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Reactivity
    • 116
    • 29
    • 21
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Primate
    Host
    • 75
    • 43
    • 20
    Mouse
    Clonality
    • 92
    • 40
    • 1
    Monoclonal
    Conjugate
    • 57
    • 15
    • 13
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin Alpha2b antibody is un-conjugated
    Application
    • 100
    • 44
    • 32
    • 27
    • 19
    • 18
    • 13
    • 13
    • 10
    • 9
    • 8
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Protein-G affinity chromatography
    Purity
    > 95 % (by SDS-PAGE)
    Clone
    HIP8
    Isotype
    IgG1
    Top Product
    Discover our top product CD41 Primary Antibody
  • Application Notes
    Flow Cytometry: (has been tested by flow cytometric analysis of human platelets. Can be used at less than or equal to 0.5 μg per 100 μL blood (per 10^6 cells). Immunohistochemistry (frozen sections).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Expiry Date
    12 months
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    CD41 / ITGA2B (CD41 Products)
    Synonyms
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    Background
    CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb
    UniProt
    P08514
    Pathways
    Integrin Complex
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