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PPM1A antibody

PPM1A Reactivity: Human, Mouse WB, IP, IHC (p), EIA Host: Mouse Monoclonal p6c7 unconjugated
Catalog No. ABIN121149
  • Target See all PPM1A Antibodies
    PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
    Reactivity
    • 37
    • 18
    • 16
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 28
    • 9
    Mouse
    Clonality
    • 29
    • 8
    Monoclonal
    Conjugate
    • 25
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PPM1A antibody is un-conjugated
    Application
    • 30
    • 18
    • 8
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects Protein Phosphatase 2C alpha (PP2C alpha).
    Purification
    Protein-G affinity chromatography
    Immunogen
    Recombinant human PP2C alpha protein
    Clone
    P6c7
    Isotype
    IgG2b
    Top Product
    Discover our top product PPM1A Primary Antibody
  • Application Notes
    ELISA. Western blot: Recommended dilution range: 1:250 approx. 1:1000. Recommended starting dilution: 1:250. Immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, containing 0.09 % Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2-8 °C for one month or at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    Expiry Date
    12 months
  • Target
    PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))
    Alternative Name
    Protein Phosphatase 1A / PPM1A (PPM1A Products)
    Synonyms
    PP2C-ALPHA antibody, PP2CA antibody, PP2Calpha antibody, pp2ca1 antibody, ppp1r13b antibody, si:ch211-253p18.1 antibody, wu:fd42g12 antibody, zgc:153820 antibody, 2310003C21Rik antibody, 2900017D14Rik antibody, AI427932 antibody, AU017636 antibody, MMPa-2 antibody, MPPa-1 antibody, Pp2c1 antibody, pp2c-alpha antibody, pp2ca antibody, pp2calpha antibody, pp2ca2 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1A antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Ab antibody, protein phosphatase 1A, magnesium dependent, alpha isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1A antibody, protein phosphatase, Mg2+/Mn2+ dependent 1A L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Aa antibody, PPM1A antibody, ppm1ab antibody, Ppm1a antibody, ppm1a.L antibody, ppm1aa antibody
    Background
    Protein phosphatase 2C(PP2Cα) is a Mn2+- or Mg2+-dependent protein serine/threonine phosphatase that inhibits the human stress-responsive p38 and JNK MAPK pathways and regulates cellular stress response in eukaryotes. The PPM (metal-dependent protein phosphatase) family of Ser/Thr protein phosphatases have recently been shown to down-regulate the stress response pathways in eukaryotes. Within the stress pathway, key signaling kinases, which are activated by protein phosphorylation, have been proposed as the in vivo substrates of PP2C, the prototypical member of the PPM family.Synonyms: PP2C-alpha, PPPM1A, Protein phosphatase 2C isoform alpha, Protein phosphatase IA
    UniProt
    P35813
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