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HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) antibody

Details for Product No. ABIN121159, Supplier: Log in to see
Antigen
  • CG8464
  • DmHtrA2
  • Dmel\\CG8464
  • HtrA2/Omi
  • Omi
  • dOmi
  • domi
  • htrA2
  • omi
  • HTRA2
  • PRSS25
  • OMI
  • PARK13
  • AI481710
  • Prss25
  • mnd2
Epitope
AA 134-458
20
15
14
9
6
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
128
36
34
1
1
1
Host
Mouse
97
31
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
6
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
97
66
50
19
17
11
3
2
1
1
1
1
1
1
Supplier
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Immunogen Recombinant human HtrA2/Omi (134-458 aa) purified from E. coli
Clone 1B3
Isotype IgG1
Purification Protein-G affinity chromatography
Alternative Name HTRA2 / PRSS25 (HTRA2 Antibody Abstract)
Background HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Recently, HtrA2 has been known to contribute both to caspase-dependent and caspase-independent cell death.Synonyms: High temperature requirement protein A2, OMI, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, mitochondrial Serine protease HTRA2
UniProt O43464
Pathways
Application Notes ELISA. Western blot (1:500 - 1:2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) antibody (ABIN121159) Western blot analysis.,.The extracts of 293T, MCF7, HT-29, HL-60, HeLa, mouse brain, ...
Background publications Zumbrunn, Trueb: "Primary structure of a putative serine protease specific for IGF-binding proteins." in: FEBS letters, Vol. 398, Issue 2-3, pp. 187-92, 1997 (PubMed).