HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) antibody

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Antigen
Synonyms CG8464, DmHtrA2, Dmel\\CG8464, HtrA2/Omi, Omi, dOmi, domi, htrA2, omi, HTRA2, PRSS25, OMI, PARK13, AI481710, Prss25, mnd2
Epitope
AA 134-458
(25), (16), (14), (10), (9), (7), (5), (4), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(151), (41), (38), (1), (1), (1)
Host
Mouse
(114), (37)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(6), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
(117), (77), (58), (22), (20), (11), (4), (3), (3), (3), (2), (2), (2), (1), (1)
Pubmed 1 reference available
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Quantity 0.1 mL
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen Recombinant human HtrA2/Omi (134-458 aa) purified from E. coli
Clone 1B3
Isotype IgG1
Purification Protein-G affinity chromatography
Alternative Name HTRA2 / PRSS25 (HTRA2 Antibody Abstract)
Background HtrA2/Omi is a mammalian serine protease at high temperatures and a chaperone at low temperature. The full-length HtrA2 is synthesized as a precursor protein and then targeted to the mitochondria where it is matured by the removal of N-terminal 133 residues. Recently, HtrA2 has been known to contribute both to caspase-dependent and caspase-independent cell death.Synonyms: High temperature requirement protein A2, OMI, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI, mitochondrial Serine protease HTRA2
UniProt O43464
Application Notes ELISA. Western blot (1:500 - 1:2,000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Supplier Images
Western Blotting (WB) image for anti-HtrA Serine Peptidase 2 (HTRA2) (AA 134-458) antibody (ABIN121159) Western blot analysis.,.The extracts of 293T, MCF7, HT-29, HL-60, HeLa, mouse brain, ...
Background publications Zumbrunn, Trueb: "Primary structure of a putative serine protease specific for IGF-binding proteins." in: FEBS letters, Vol. 398, Issue 2-3, pp. 187-92, 1997 (PubMed).

Catalog No. ABIN121159
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