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GDNF Family Receptor alpha 2 (GFRA2) (C-Term) antibody

Details for Product No. ABIN121837, Supplier: Login to see
Antigen
  • DKFZP459C0228
  • GFRA2
  • ntnra
  • retl2
  • trnr2
  • gdnfrb
  • nrtnr-alpha
  • gfra2
  • GDNFRB
  • NRTNR-ALPHA
  • NTNRA
  • RETL2
  • TRNR2
  • Retl2
  • NTNRALPHA
Epitope
C-Term
23
15
13
6
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
73
34
34
1
1
Host
Rabbit
69
2
1
1
Clonality
Polyclonal
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
57
31
11
6
4
3
3
2
1
Supplier
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Immunogen Synthetic peptide from C-terminus of human GFR alpha-2
Purification Ion exchange chromatography
Alternative Name GFRA2 / GDNFR-beta (GFRA2 Antibody Abstract)
Background Neurturin is a member of the GDNF family, and has an important role in the control of vertebrate neuron survival and differentiation. GRF alpha-2 is a 52kD glycoprotein, and is a GPI-linked cell surface receptor.Synonyms: GDNF family receptor alpha-2, GDNF receptor beta, GDNFRB, GFR-alpha-2, Neurturin receptor alpha, RET ligand 2, RETL2, TGF-beta-related neurotrophic factor receptor 2, TRNR2
UniProt O00451
Pathways
Application Notes Western Blot: 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 mg/mL
Buffer PBS containing 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months
Background publications Buj-Bello, Adu, Piñón et al.: "Neurturin responsiveness requires a GPI-linked receptor and the Ret receptor tyrosine kinase." in: Nature, Vol. 387, Issue 6634, pp. 721-4, 1997 (PubMed).

Klein, Sherman, Ho et al.: "A GPI-linked protein that interacts with Ret to form a candidate neurturin receptor." in: Nature, Vol. 387, Issue 6634, pp. 717-21, 1997 (PubMed).