G Protein-Coupled Receptor 116 antibody (Cytoplasmic Domain)

Catalog No. ABIN122116

Product Details anti-G Protein-Coupled Receptor 116 Antibody

Target: G Protein-Coupled Receptor 116 (GPR116)

Binding Specificity: Cytoplasmic Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This G Protein-Coupled Receptor 116 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with G Protein-Coupled Receptor GPR116 (family: GPCR, subfamily: Orphan-B)

Cross-Reactivity (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Immunohistochemistry with formalin fixed paraffin embedded tissues: 6 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for G Protein-Coupled Receptor 116

Target: G Protein-Coupled Receptor 116 (GPR116)

Alternative Name: GPR116 (GPR116 Products)

Synonyms: GPR116 antibody, KPG_001 antibody, 8430401C09Rik antibody, 9330185D23 antibody, AI528491 antibody, mKIAA0758 antibody, Gprhep antibody, Ig-Hepta antibody, G protein-coupled receptor 116 antibody, adhesion G protein-coupled receptor F5 antibody, adhesion G protein-coupled receptor F1 antibody, GPR116 antibody, ADGRF5 antibody, adgrf1 antibody, Adgrf5 antibody

Background: GPR116/KIAA0758 is an Orphan-B GPCR with an unknown ligand. GPR116 has two immunoglobulin-like repeats and a SEA box. RT-PCR analysis from the KIAA database suggests that KIAA0758 is expressed in heart, kidney, lung and ovary. ESTs have been isolated from brain, breast, eye, heart, kidney, liver, liver/spleen, lung, nasopharyngeal, spleen, and testis libraries.Synonyms: G-protein coupled receptor 116, KIAA0758

Gene ID: 221395

UniProt: Q8IZF2

Pathways: Carbohydrate Homeostasis