HLA-DR-gamma (CD74) antibody (PE)

Antigen: HLA-DR-gamma (CD74)

Synonyms: DHLAG, HLADG, Ia-GAMMA, Ii, CLIP

Clonality: Monoclonal (MEM-12)

Host: Mouse

Reactivity: Human

Conjugate: PE

Application: Flow Cytometry (FACS)

Catalog no.: ABIN125743

Additional Information

Alternative name: HLA-DR

Immunogen: thymocyte membrane

Isotype: IgG1

Clone: MEM-12

Specificity: The antibody MEM-12 recognizes common epitope on human HLA-DR which is dependenton the association of alpha and beta chains. DR is the isotype of human MHC Class IImolecules expressed on antigen-presenting cells (APC, dendritic cells, B lymphocytes,monocytes, macrophages).

Application Details

Application Notes: The reagent is designed for Flow Cytometry analysis of human blood cells using 20 µl reagent / 100 µl of whole blood or 10 6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.

Buffer: The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azideand 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.

Storage: Store in the dark at 2-8 o C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.Short-term exposure to room temperature should not affect the quality of the reagent.However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.

Research Area: Major Histocompatibility Complex (MHC), CD Antigens, Surface Receptors of Immune Cells

Restrictions: For Research Use only

Images

Flow Cytometry analysis

Publications

Publications: Simpson, McFarlin, McSporran et al.: "Toll-like receptor expression on classic and pro-inflammatory blood monocytes after acute exercise in humans." in: Brain, behavior, and immunity, Vol. 23, Issue 2, pp. 232-9, 2009 (PubMed).