HDAC5 antibody
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- Target See all HDAC5 Antibodies
- HDAC5 (Histone Deacetylase 5 (HDAC5))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Specificity
- The antibody detects ~124 kDa histone deacetylase 5. It does not cross-react with other HDAC proteins including HDAC1, 2, 3, 4, 6, 7, and 8.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse and Rat (Weak).
- Purification
- Affinity Chromatography
- Immunogen
- Synthetic peptide surrounding amino acid 575 of Human HDAC-5
- Top Product
- Discover our top product HDAC5 Primary Antibody
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- Application Notes
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Western Blot: 1 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- PBS, pH 7.2, 0.01 % Thimerosal, 0.5 % BSA, 30 % Glycerol
- Preservative
- Thimerosal (Merthiolate)
- Precaution of Use
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Store undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Target
- HDAC5 (Histone Deacetylase 5 (HDAC5))
- Alternative Name
- HDAC5 (HDAC5 Products)
- Synonyms
- HD5 antibody, NY-CO-9 antibody, AI426555 antibody, Hdac4 antibody, mHDA1 antibody, mKIAA0600 antibody, ATHDA5 antibody, HDA5 antibody, MAF19.7 antibody, MAF19_7 antibody, histone deacetylase 5 antibody, histone deacetylase 5 antibody, HDAC5 antibody, Hdac5 antibody, HDA05 antibody, hdac5 antibody
- Background
- HDAC5 is a member of the class II mammalian histone deacetylase family, which is structurally related to yeast HDA1. Human HDAC5 is composed of 1122 amino acid residues. The deacetylase domain of HDAC5 is located at the C-terminal half of the molecule. The N-terminal non-deacetylase domain does not show any significant homology with any published sequence. Both domains are required for HDAC5-mediated repression of gene transcription. HDAC5 interacts with a growing number of transcriptional factors including MEF2A as well as other HDAC proteins. The interacting complexes bind to specific regions of chromatin and regulate gene transcription in these regions.Synonyms: Antigen NY-CO-9, HD5, Histone deacetylase 5, KIAA0600
- Gene ID
- 10014
- NCBI Accession
- NP_001015053
- UniProt
- Q9UQL6
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process
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