DICER1 antibody

Catalog No. ABIN127311

The Rabbit Polyclonal anti-DICER1 antibody (ABIN127311) specifically detects DICER1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DICER1 antibody (ABIN127311)

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DICER1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DICER1 Antibody

Specificity: This antibody detects Dicer.

Purification: Protein A affinity purified

Immunogen: Synthetic peptide surrounding amino acid 1902 of human Dicer

Application Details

Application Notes: Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.2 mg/mL

Buffer: PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C/-80 °C

Storage Comment: Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.

Target Details for DICER1

Target: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Alternative Name: DICER1

Background: Dicer is an RNaseIII-like enzyme which cleaves double-stranded RNA into 21-23 ny RNAs. These RNAs are referred to as siRNA (short interfering RNA). It is believed to be essential in siRNA-mediated gene suppression.Synonyms: DCR1, Endoribonuclease Dicer, HERNA, Helicase MOI, Helicase with RNase motif, KIAA0928

Gene ID: 23405

NCBI Accession: NP_085124

UniProt: Q9UPY3

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization