SLC7A5 antibody (AA 101-200)
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- Target See all SLC7A5 Antibodies
- SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
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Binding Specificity
- AA 101-200
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Reactivity
- Human, Mouse, Rat, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC7A5 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Mouse, Pig, Rat
- Predicted Reactivity
- Dog,Cow,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SLC7A5
- Isotype
- IgG
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- Application Notes
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults." in: The American journal of clinical nutrition, Vol. 104, Issue 4, pp. 1014-1022, (2016) (PubMed).
: "Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers." in: Science (New York, N.Y.), Vol. 353, Issue 6304, pp. 1161-5, (2016) (PubMed).
: "
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Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults." in: The American journal of clinical nutrition, Vol. 104, Issue 4, pp. 1014-1022, (2016) (PubMed).
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- Target
- SLC7A5 (Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5 (SLC7A5))
- Alternative Name
- SLC7A5 (SLC7A5 Products)
- Synonyms
- 4F2LC antibody, CD98 antibody, D16S469E antibody, E16 antibody, LAT1 antibody, MPE16 antibody, hLAT1 antibody, D0H16S474E antibody, TA1 antibody, JHI-21 antibody, SLC7A5 antibody, LAT-1 antibody, slc7a5a antibody, 4F2 antibody, 4F2HC antibody, AI314110 antibody, Cd98 antibody, Ly-10 antibody, Ly-m10 antibody, Ly10 antibody, Mdu1 antibody, Mgp-2hc antibody, NACAE antibody, solute carrier family 7 member 5 antibody, solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 antibody, solute carrier family 7 (amino acid transporter light chain, L system), member 5 antibody, solute carrier family 7 member 5 S homeolog antibody, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 antibody, SLC7A5 antibody, Slc7a5 antibody, slc7a5.S antibody, Slc3a2 antibody
- Background
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Synonyms: Large neutral amino acids transporter small subunit 1, 4F2 light chain, 4F2 LC, 4F2LC, CD98 light chain, Integral membrane protein E16, L-type amino acid transporter 1, hLAT1, Solute carrier family 7 member 5, y+ system cationic amino acid transporter, SLC7A5, CD98LC, LAT1, MPE16
Background: Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Involved in cellular amino acid uptake. Acts as an amino acid exchanger. Involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Plays a role in neuronal cell proliferation (neurogenesis) in brain. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. Involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. May play an important role in high-grade gliomas. Mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. Acts as the major transporter of tyrosine in fibroblasts.
- Gene ID
- 8140
- UniProt
- Q01650
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