TANC1 antibody (AA 31-130) (Cy5)
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- Target See all TANC1 Antibodies
- TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
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Binding Specificity
- AA 31-130
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TANC1 antibody is conjugated to Cy5
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human TANC1
- Isotype
- IgG
- Top Product
- Discover our top product TANC1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
- Alternative Name
- TANC1 (TANC1 Products)
- Synonyms
- ROLSB antibody, TANC antibody, 1200003E16Rik antibody, Tanc antibody, mKIAA1728 antibody, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 antibody, TANC1 antibody, Tanc1 antibody
- Background
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Synonyms: ROLSB, Protein TANC1, Rolling pebbles homolog B, TANC, Tanc1, TANC1_HUMAN, Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1, Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1, TPR domain ankyrin repeat and coiled coil containing.
Background: TANC (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein), also known as TANC1, is a 1,861 amino acid postsynaptic cell membrane protein that contains eleven ANK repeats, three TPR repeats and belongs to the TANC family. Considered a scaffolding component in the postsynaptic density, TANC interacts with TNIK, SAPAP1, Alpha-internexin, CaMKII, NMDA 2 and GluR-1. It is also thought that TANC interacts directly with SAP 97, PSD-95 and Homer. Upon stimulation by Rap 2, MINK1 and TNIK may phosphorylate TANC. The TANC gene encodes two alternatively spliced isoforms, contains approximately 264,025 bases and maps to human chromosome 2q24.2. Making up approximately 8 % of the human genome, chromosome 2 consists of 237 million bases and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.
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