CACYBP antibody (AA 61-95) (HRP)

Catalog No. ABIN1412318

Product Details anti-CACYBP Antibody (HRP)

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Binding Specificity: AA 61-95

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CACYBP antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CACYBP/S100A6BP

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CACYBP

Target: CACYBP (Calcyclin Binding Protein (CACYBP))

Alternative Name: CACYBP/S100A6BP (CACYBP Products)

Synonyms: zgc:76993 antibody, CACYBP antibody, sip antibody, gig5 antibody, pnas-107 antibody, s100a6bp antibody, T1P2.12 antibody, T1P2_12 antibody, GIG5 antibody, RP1-102G20.6 antibody, S100A6BP antibody, SIP antibody, calcyclin binding protein antibody, calcyclin binding protein, putative antibody, Calcyclin binding protein, putative antibody, SGS domain-containing protein antibody, calcyclin binding protein L homeolog antibody, cacybp antibody, CACYBP antibody, PB000926.02.0 antibody, PCHAS_145490 antibody, PVX_100855 antibody, PKH_145680 antibody, AT1G30070 antibody, cacybp.L antibody, Cacybp antibody

Background:

Synonyms: SIAH Interacting Protein, CACYBP, Calcyclin binding protein, GIG 5, GIG5, Growth inhibiting gene 5, Calcyclin-binding protein, Siah-interacting protein, Growth inhibiting gene 5 protein, hCacyBP, MGC87971, PNAS 107, PNAS107, RP1 102G20.6, S100A6 binding protein, S100A6BP, SIP.

Background: CacyBP is a 228 amino acid protein encoded by the human gene CACYBP. CacyBP is primarily a nuclear protein that contains one CS domain and one SGS domain. CacyBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CacyBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.

Pathways: Response to Growth Hormone Stimulus