SCN2B antibody (AA 65-180) (Cy7)
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- Target See all SCN2B Antibodies
- SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))
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Binding Specificity
- AA 65-180
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCN2B antibody is conjugated to Cy7
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human SCN2B
- Isotype
- IgG
- Top Product
- Discover our top product SCN2B Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SCN2B (Sodium Channel, Voltage-Gated, Type II, beta (SCN2B))
- Alternative Name
- SCN2B (SCN2B Products)
- Synonyms
- SCNB2 antibody, 2810451E09Rik antibody, AI840361 antibody, Gm183 antibody, SCN2B antibody, sodium voltage-gated channel beta subunit 2 antibody, sodium channel, voltage-gated, type II, beta antibody, sodium voltage-gated channel beta subunit 2 L homeolog antibody, SCN2B antibody, Scn2b antibody, scn2b.L antibody, scn2b antibody
- Background
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Synonyms: Neuronal voltage gated sodium channel beta 2 subunit, Scn 2b, Scn2b, SCN2B_HUMAN, Sodium channel beta 2 subunit, Sodium channel subunit beta 2, Sodium channel subunit beta-2, Sodium channel voltage gated type II beta, Sodium channel voltage gated type II beta polypeptide.
Background: Voltage-gated sodium channels are selective ion channels that regulate the permeability of sodium ions in excitable cells. During the propagation of an action potential, sodium channels allow an influx of sodium ions, which rapidly depolarizes the cell. Na+ CP type II beta(sodium channel, voltage-gated, type II, beta), also known as SCN2B, is a 215 amino acid single-pass type I membrane protein that plays a critical role in the expression and assembly of the heterotrimeric complex of the sodium channel and interacts with Tenascin-R to influence the clustering and regulation of sodium channels at nodes of Ranvier. Expressed specifically in brain, Na+ CP type II beta contains one Ig-like C2-type (immunoglobulin-like) domain and is encoded by a gene that maps to human chromosome 11q23.3 and mouse chromosome 9 A5.2.
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