PD-L1 antibody (FITC)
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- Target See all PD-L1 Antibodies
- PD-L1 (CD274 (PD-L1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PD-L1 antibody is conjugated to FITC
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Application
- Flow Cytometry (FACS)
- Specificity
- This antibody reacts with human CD279/PD-1.
- Purification
- Protein A agarose beads
- Immunogen
- Human recombinant CD279/PD-1
- Clone
- J110
- Isotype
- IgG1
- Top Product
- Discover our top product PD-L1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.05 mg/mL
- Buffer
- PBS, 0.09 % NaN3, 1 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store at 2-8 °C.
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- Target
- PD-L1 (CD274 (PD-L1))
- Alternative Name
- CD274 / PDL1 (PD-L1 Products)
- Synonyms
- B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
- Background
- Human PD-1 (programmed death-1) is a 55KDa member of the immunoglobulin superfamily that is induced in cells undergoing apoptosis. The PD-1 protein contains an immunoreceptor tyrosine-based inhibitory motif and is expressed predominantly on activated T and B lymphocytes. PD-1 plays a key role in peripheral tolerance and autoimmune disease and is thought to be involved in the maintenance of peripheral self-tolerance by serving as a negative regulator of immune responses. Two novel members of the B7 family have been identified as PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and up-regulation on activated antigen-presenting cells.Synonyms: B7 homolog 1, B7H1, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, Programmed death ligand 1
- Gene ID
- 29126
- NCBI Accession
- NP_054862
- UniProt
- Q9NZQ7
- Pathways
- Cancer Immune Checkpoints
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