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MFGE8 antibody
MFGE8
Reactivity: Mouse
WB, IHC (fro)
Host: Hamster
Monoclonal
18A2-G10
unconjugated
Product Details anti-MFGE8 Antibody
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Target
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MFGE8
(Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
Reactivity
All reactivities for MFGE8 antibodies
Mouse
Host
All hosts for MFGE8 antibodies
Hamster
Clonality
All clonalities for MFGE8 antibodies
Monoclonal
Conjugate
All conjugates for MFGE8 antibodies
This MFGE8 antibody is un-conjugated
Application
All applications for MFGE8 antibodies
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
Specificity
This antibody reacts with MFG-E8 short and long forms.
Cross-Reactivity (Details)
Species reactivity (tested):Mouse.
Purification
Protein A agarose
Immunogen
Recombinant mouse MFG-E8
Clone
18A2-G10
Isotype
IgG
Top Product
Discover our top product MFGE8 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS containing 50 % Glycerol, pH 7.2, None
Preservative
Without preservative
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Upon receipt, store (in aliquots) at -20 °C.
Target Details for MFGE8
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Target
MFGE8
(Milk Fat Globule-EGF Factor 8 Protein (MFGE8))
Alternative Name
Lactadherin (MFGE8 Products )
Synonyms
BA46 antibody, EDIL1 antibody, HMFG antibody, HsT19888 antibody, MFG-E8 antibody, MFGM antibody, OAcGD3S antibody, SED1 antibody, SPAG10 antibody, hP47 antibody, ba46 antibody, edil1 antibody, oacgd3s antibody, MGC75581 antibody, hst19888 antibody, MGC145109 antibody, MFGE8 antibody, mfge8 antibody, zgc:154157 antibody, MGC99228 antibody, AA408458 antibody, AI325141 antibody, Mfgm antibody, P47 antibody, lactadherin antibody, AGS antibody, MFGME8 antibody, MFGMP-E8 antibody, im:6895406 antibody, mfge8l antibody, zgc:110846 antibody, milk fat globule-EGF factor 8 protein antibody, milk fat globule-EGF factor 8 protein b antibody, milk fat globule-EGF factor 8 protein L homeolog antibody, milk fat globule-EGF factor 8 protein a antibody, MFGE8 antibody, mfge8 antibody, mfge8b antibody, mfge8.L antibody, Mfge8 antibody, mfge8a antibody
Background
Apoptotic cells are rapidly removed by phagocytosis to clear the living cells and tissues of intracellular materials being released from dying cells. Phagocytes recognize apoptotic cells through milk fat globule-EGF-factor 8 (MFG-E8). MFG-E8 is a secreted glycoprotein from thioglycollate-elicited macrophages and bind to phosphatidylserine exposed on the cell surface of apoptotic cells, then bind strongly to cells expressing avß3 integrin via its RGD (arginine-glycine-aspartate) motif. Thus, MFG-E8 is an important protein to mediate the engulfment of apoptotic cells by activated macrophages.Synonyms: Breast epithelial antigen BA46, HMFG, MFGE8, MFGM, Milk fat globule-EGF factor 8
Gene ID
4240
NCBI Accession
NP_001108086
UniProt
Q08431
Pathways
SARS-CoV-2 Protein Interactome
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