Autophagy Related 4D, Cysteine Peptidase (ATG4D) (N-Term), (AA 49-79) antibody

Details for Product No. ABIN1449592
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Antigen
Synonyms APG4-D, APG4D, AUTL4, 9830134P12Rik, Apg4d, Atg4dl, Autl4, apg4d
Epitope
N-Term, AA 49-79
(12), (12), (12), (7), (4), (4), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(84), (59), (40), (38), (38), (36)
Host
Rabbit
(82), (10), (3), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(6), (6), (6), (4), (4), (4), (4), (4), (4), (4), (4), (2), (2), (2)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
(56), (40), (26), (18), (16), (6), (5), (3)
Pubmed 3 references available
Quantity 0.4 mL
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN1449592
357.50 $
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Immunogen KLH conjugated synthetic peptide between 49-79 amino acids from the N-terminal region of Human ATG4D
Specificity This antibody recognizes Human and Mouse ATG4D (N-term). Other species not tested.
Purification Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
Alternative Name APG4D / ATG4D
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases.
Alternate names: AUT-like 4 cysteine endopeptidase, AUTL4, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D
Gene ID 84971
NCBI Accession NP_116274
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09% (w/v) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Expiry Date 12 months
Background publications Mariño, Uría, Puente et al.: "Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy." in: The Journal of biological chemistry, Vol. 278, Issue 6, pp. 3671-8, 2003 (PubMed).

Lamesch, Li, Milstein et al.: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007 (PubMed).

Betin, Lane: "Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis." in: Journal of cell science, Vol. 122, Issue Pt 14, pp. 2554-66, 2009 (PubMed).

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