ATG12 antibody (N-Term)
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- Target See all ATG12 Antibodies
- ATG12 (Autophagy Related 12 (ATG12))
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Binding Specificity
- AA 44-73, N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ATG12 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificity
- This antibody recognizes Human APG12L (N-term). Other species not tested.
- Purification
- Saturated Ammonium Sulfate precipitation followed by dialysis against PBS
- Immunogen
- KLH conjugated synthetic peptide between 44~73 amino acids from the N-term of Human APG12L Genename: ATG12
- Isotype
- Ig Fraction
- Top Product
- Discover our top product ATG12 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- ATG12 (Autophagy Related 12 (ATG12))
- Alternative Name
- ATG12 / APG12 (ATG12 Products)
- Synonyms
- APG12 antibody, APG12L antibody, FBR93 antibody, HAPG12 antibody, Apg12l antibody, AUTOPHAGY 12 antibody, AUTOPHAGY 12 B antibody, CG10861 antibody, Dmel\\CG10861 antibody, atg12 antibody, ATG12 antibody, apg12 antibody, DDBDRAFT_0185323 antibody, DDBDRAFT_0191412 antibody, DDB_0185323 antibody, DDB_0191412 antibody, 4931423H11Rik antibody, A330058M13Rik antibody, Atg12l antibody, AO090001000593 antibody, autophagy related 12 antibody, Ubiquitin-like superfamily protein antibody, Atg12p antibody, autophagy protein antibody, ubiquitin-like protein ATG12B antibody, autophagy associated protein Atg12 antibody, Autophagy-related 12 antibody, ATG12 autophagy related 12 homolog (S. cerevisiae) antibody, ATG12 autophagy related 12 homolog (S. cerevisiae) pseudogene antibody, autophagy associated ubiquitin-like modifier Atg12 antibody, hypothetical protein antibody, Autophagy-related protein 12 (Autophagy-related ubiquitin-like modifier ATG12) antibody, autophagy protein 12 antibody, autophagy related 12 S homeolog antibody, autophagy-related protein 12 antibody, ATG12 antibody, Atg12 antibody, APG12B antibody, APG12 antibody, LOC9321066 antibody, apg12 antibody, atg12 antibody, LOC743425 antibody, CAALFM_C113950CA antibody, atg12.S antibody, ANI_1_922094 antibody, AOR_1_1064164 antibody
- Background
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). APG12L is the human homolog of yeast APG12, a ubiquitin-activating enzyme E1-like protein essential for the conjugation system that mediates membrane fusion in autophagy.Synonyms: APG12-like, APG12L, Autophagy-related protein 12, Ubiquitin-like protein ATG12
- Molecular Weight
- 15113 Da
- Gene ID
- 9140
- NCBI Accession
- NP_004698
- Pathways
- Autophagy
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