AKAP5 antibody (Middle Region)

Catalog No. ABIN1449866

Product Details anti-AKAP5 Antibody

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KQFLISAENE QVGVFANDNG FEDRTSEQYE TLLIETASSL VKNAIQLSIE

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, BovineSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human AKAP5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for AKAP5

Target: AKAP5 (A Kinase (PRKA) Anchor Protein 5 (AKAP5))

Alternative Name: AKAP5 (AKAP5 Products)

Synonyms: AKAP5 antibody, AKAP75 antibody, AKAP79 antibody, H21 antibody, AKAP antibody, P75 antibody, 3526401B18Rik antibody, AKAP 150 antibody, AKAP-5 antibody, AKAP150 antibody, BB098886 antibody, Gm258 antibody, P150 antibody, Akap79 antibody, A kinase (PRKA) anchor protein 5 antibody, A-kinase anchoring protein 5 antibody, AKAP5 antibody, Akap5 antibody

Target Type: Viral Protein

Background: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP5 is a member of the AKAP family. It binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT.Synonyms: A-kinase anchor protein 5, A-kinase anchor protein 79 kDa, AKAP79, cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein

Gene ID: 9495

NCBI Accession: NP_004848

Pathways: cAMP Metabolic Process