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AKAP5 Products

(A Kinase (PRKA) Anchor Protein 5 (AKAP5))
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to the RII-beta regulatory subunit of PKA, and also to protein kinase C and the phosphatase calcineurin. It is predominantly expressed in cerebral cortex and may anchor the PKA protein at postsynaptic densities (PSD) and be involved in the regulation of postsynaptic events. It is also expressed in T lymphocytes and may function to inhibit interleukin-2 transcription by disrupting calcineurin-dependent dephosphorylation of NFAT. [provided by RefSeq, Jul 2008].

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Featured AKAP5 Categories

AKAP5 Antibodies

High quality antibodies with extensive validation data.

AKAP5 ELISA Kits

Reliable ELISA kits for a wide range of species.

AKAP5 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AKAP5 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IF, ICC
Validations
  • (3)
Cat. No. ABIN6257661
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7142909
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (2)
Cat. No. ABIN7262365
Quantity 200 μL
Datasheet Datasheet

Recommended AKAP5 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648126
Quantity 96 tests
Datasheet Datasheet

Recommended AKAP5 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344721
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344723
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7422979
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our AKAP5 products

Schillace, Andrews, Liberty, Davey, Carr: "Identification and characterization of myeloid translocation gene 16b as a novel a kinase anchoring protein in T lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 4, pp. 1590-9, (2002) (PubMed).

Jicha, Weaver, Lane, Vianna, Kress, Rockwood, Davies: "cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 19, Issue 17, pp. 7486-94, (1999) (PubMed).

Coghlan, Perrino, Howard, Langeberg, Hicks, Gallatin, Scott: "Association of protein kinase A and protein phosphatase 2B with a common anchoring protein." in: Science (New York, N.Y.), Vol. 267, Issue 5194, pp. 108-11, (1995) (PubMed).

Carr, Stofko-Hahn, Fraser, Cone, Scott: "Localization of the cAMP-dependent protein kinase to the postsynaptic densities by A-kinase anchoring proteins. Characterization of AKAP 79." in: The Journal of biological chemistry, Vol. 267, Issue 24, pp. 16816-23, (1992) (PubMed).

Synonyms and alternative names related to AKAP5

A kinase (PRKA) anchor protein 5 (AKAP5), A-kinase anchoring protein 5 (AKAP5), A kinase (PRKA) anchor protein 5 (Akap5), A-kinase anchoring protein 5 (Akap5), 3526401B18Rik, AKAP, AKAP-5, AKAP5, AKAP75, AKAP79, Akap79, AKAP 150, AKAP150, BB098886, Gm258, H21, P75, P150

Protein level used designations for AKAP5

  • A kinase (PRKA) anchor protein 5
  • A-kinase anchor protein 5
  • A-kinase anchor protein 5-like
  • a-kinase anchor protein 5-like
  • A-kinase anchor protein 79 kDa
  • A-kinase anchor protein, 79kDa
  • A-kinase anchoring protein 75/79
  • AKAP 79
  • AKAP-5
  • cAMP-dependent protein kinase regulatory subunit II high affinity binding protein
  • cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein
  • A-kinase anchor protein 75 kDa
  • AKAP 75
  • anchor protein regulatory subunit (AKAP75)
  • A-kinase anchor protein 150 kDa
  • AKAP 150
  • RII-B-binding protein
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