Dopamine d2 Receptor antibody
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- Target See all Dopamine d2 Receptor (DRD2) Antibodies
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dopamine d2 Receptor antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- Reacts with Human Dopamine Receptor D2 (family: GPCR, subfamily: Dopamine). BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except ZNF57 (42 %).
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Immunoaffinity Chromatography
- Top Product
- Discover our top product DRD2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))
- Alternative Name
- Dopamine D2 Receptor (DRD2 Products)
- Synonyms
- D2DR antibody, D2R antibody, drd2b antibody, d2r2 antibody, Drd-2 antibody, d2dr antibody, d2r antibody, drd2 antibody, drd2-B antibody, DRD2 antibody, D2 antibody, CG18741 antibody, CG7569 antibody, DAMB antibody, DDR2 antibody, DOPR2 antibody, DOPR99B antibody, Dar2 antibody, Dmel\\CG18741 antibody, DopD1 antibody, DopR99B antibody, DopRII antibody, dopamine receptor D2 antibody, dopamine receptor D2 like antibody, dopamine receptor D2 L homeolog antibody, dopamine receptor D2 S homeolog antibody, Dopamine 1-like receptor 2 antibody, DRD2 antibody, drd2l antibody, drd2 antibody, Drd2 antibody, drd2.L antibody, drd2.S antibody, Dop1R2 antibody
- Background
- The DRD2 Dopamine Receptor is involved in the neuromodulation of appetitive behaviors. DRD2 may be linked to alcoholism and other substance-use disorders. Mutations in DRD2 in mice lead to the suppression of reward behavior with morphine and to the reduction of spontaneous movements, a phenotype resembling Parkinson's disease. Three alternatively spliced isoforms have been identified. DRD2 has been reported to be expressed in various regions of the brain, as well as in aorta, artery, eye, and spinal cord. ESTs have been isolated from normal pituitary and in brain, colon, lung, pancreas, and skeletal muscle cancer libraries.Synonyms: D(2) dopamine receptor, DRD2
- Gene ID
- 1813
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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