GRIK5 antibody (AA 969-980)

Catalog No. ABIN1492538

Product Details anti-GRIK5 Antibody

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Binding Specificity: AA 969-980

Reactivity: Human, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This GRIK5 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human GRIK5.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Dog (100%) Bovine (92%) Mouse, Rat (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-GPAGPRELAEHE from the C-terminus of human GRIK5 (NP_002079.3). Percent identity by BLAST analysis: Human, Chimpanzee, Dog (100%), Bovine (92%), Mouse, Rat (83%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000)

Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx. 26  kDa band in Human Brain (Frontal Cortex and Hippocampus) lysates after 1 μg/mL antibody staining. Please note that currently we can not find an explanation in the literature for the band we observe given the calculated size of 109  kDa according to NP_002079.3. The 26  kDa band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GRIK5

Target: GRIK5 (Glutamate Receptor, Ionotropic, Kainate 5 (GRIK5))

Alternative Name: GRIK5 / KA2 (GRIK5 Products)

Synonyms: EAA2 antibody, GRIK2 antibody, GluK5 antibody, KA2 antibody, GRIK5 antibody, Glur6 antibody, ka2 antibody, eaa2 antibody, GluRgamma2 antibody, iGlu5 antibody, glutamate ionotropic receptor kainate type subunit 5 antibody, glutamate receptor, ionotropic, kainate 5 antibody, glutamate ionotropic receptor kainate type subunit 2 antibody, glutamate receptor, ionotropic, kainate 5 L homeolog antibody, glutamate receptor, ionotropic, kainate 5 (gamma 2) antibody, GRIK5 antibody, GRIK2 antibody, grik5 antibody, grik5.L antibody, Grik5 antibody

Background: Name/Gene ID: GRIK5
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIK5, EAA2, Glutamate receptor KA2, KA2, GluK5, Glutamate receptor KA-2

Gene ID: 2901

NCBI Accession: NP_002079

UniProt: Q16478

Pathways: Carbohydrate Homeostasis, Synaptic Membrane, Maintenance of Protein Location, Synaptic Vesicle Exocytosis