Retinoblastoma Binding Protein 4 antibody (C-Term)

Catalog No. ABIN1544226

Product Details anti-Retinoblastoma Binding Protein 4 Antibody

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Retinoblastoma Binding Protein 4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TAKISDFSWN PNEPWVICSV SEDNIMQVWQ MAENIYNDED PEGSVDPEGQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against Rbbp4. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Rbbp4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 425 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Retinoblastoma Binding Protein 4

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Alternative Name: Rbbp4 (RBBP4 Products)

Synonyms: NURF55 antibody, RBAP48 antibody, 154659_at antibody, 55 antibody, CAF-1 antibody, CAF1 antibody, CAF1-55 antibody, CAF1p55 antibody, CG4236 antibody, Caf-1 antibody, Caf1/p55 antibody, Caf1p55 antibody, Dmel\\CG4236 antibody, MSI1/RbAp48/CAC3/LIN-53 antibody, NURF antibody, NURF-55 antibody, Nurf antibody, Nurf 55 antibody, Nurf-55 antibody, Nurf55 antibody, P55 antibody, RbAp48 antibody, S(ls)3 antibody, caf-1 antibody, caf1 antibody, caf1 p55 antibody, d-CAF1 antibody, dCAF-1 antibody, dCAF-1 p55 antibody, dNURF antibody, p55 antibody, p55 CAF1 antibody, p55/NURF-55 antibody, p55CAF1 antibody, nurf55 antibody, rbap48 antibody, xrbbp4 antibody, mRbAp48 antibody, RBBP4 antibody, rbb4-2 antibody, zgc:55349 antibody, zgc:77854 antibody, wu:fb33a09 antibody, wu:fb40e10 antibody, RBBP-4 antibody, rbbp4 antibody, M4E13.110 antibody, M4E13_110 antibody, MULTICOPY SUPPRESSOR OF IRA1 3 antibody, NFC3 antibody, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP C 3 antibody, RB binding protein 4, chromatin remodeling factor antibody, Chromatin assembly factor 1, p55 subunit antibody, retinoblastoma binding protein 4 antibody, retinoblastoma binding protein 4, chromatin remodeling factor antibody, retinoblastoma binding protein 4 L homeolog antibody, Transducin family protein / WD-40 repeat family protein antibody, retinoblastoma binding protein 4 S homeolog antibody, RBBP4 antibody, Caf1-55 antibody, rbbp4 antibody, Rbbp4 antibody, rbbp4.L antibody, MSI3 antibody, rbbp4.S antibody

Background: Rbbp4 is a core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair, the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression, the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling, and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development, and the NURF (nucleosome remodeling factor) complex.
Alias Symbols: mRbAp48
Protein Interaction Partner: L3mbtl2, E130012A19Rik, Hdac1, Nanog, Suz12, Tcf3, Runx1, HIST3H3, Kdm2b, Rnf2, Mta2, Gata1, Ezh1, Sall4, Esrrb, Mtf2, Jarid2, Ezh2, Eed,
Protein Size: 425

Molecular Weight: 47 kDa

Gene ID: 19646

NCBI Accession: NM_009030, NP_033056

UniProt: Q60972

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus