HCK antibody (C-Term)
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- Target See all HCK Antibodies
- HCK (Hemopoietic Cell Kinase (HCK))
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Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HCK antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LVKLHAVVTK EPIYIITEFM AKGSLLDFLK SDEGSKQPLP KLIDFSAQIA
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against HCK. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human HCK
- Top Product
- Discover our top product HCK Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 504 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HCK (Hemopoietic Cell Kinase (HCK))
- Alternative Name
- HCK (HCK Products)
- Synonyms
- laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
- Background
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The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.
Alias Symbols: JTK9, p59Hck, p61Hck
Protein Interaction Partner: NOTCH2NL, KRTAP10-9, KRT40, GOPC, MTUS2, SPRR2A, STAT3, ACTB, Mbp, MED28, RUFY1, WNT2, HSP90AA1, ERBB3, ABL2, CBL, APP, PAK2, nef, TNK2, ADAM15, CREBBP, FASLG, SH3KBP1, KHDRBS1, MYC, UBC, SRC, MAP4K5, CHST15, ELMO1, SF3B3, EVL, IRF2BPL, SH3BP1, INPP5D, AG
Protein Size: 504 - Molecular Weight
- 55 kDa
- Gene ID
- 3055
- NCBI Accession
- NM_001172131, NP_001165602
- UniProt
- P08631
- Pathways
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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