Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Histone acetyltransferases (HATs) have been implicated in a number of cellular functions including gene regulation, DNA synthesis, and repair. Histone acetyltransferases and deacetylases are, respectively, the enzymes devoted to the addition and removal of acetyl groups from lysine residues on the histone N-terminal tails. The enzymes exert fundamental roles in developmental processes and their deregulation has been linked to the progression of diverse human disorders, including cancer.Synonyms: HBO1, HBOa, Histone acetyltransferase MYST2, Histone acetyltransferase binding to ORC1, MOZ, SAS2, TIP60 protein 2, YBF2/SAS3